Background Policosanol is a mixture of higher primary aliphatic alcohols isolated from sugar
cane wax, whose main component is octacosanol. The mixture has been shown to lower …

Very long chain fatty alcohols obtained from plant waxes and beeswax have been reported
to lower plasma cholesterol in humans. This review discusses nutritional or regulatory …

BACKGROUND: Cholesterol biosynthesis is strictly controlled by 3-hydroxy-3-methylglutaryl
Coenzyme A (HMG-CoA) reductase. METHODS: Transfer of cultured fibroblasts to a lipid …

Introduction This study was undertaken to evaluate the efficacy, safety, and tolerability of
policosanol, a new cholesterol‐lowering drug, in patients with type II hypercholesterolemia …

Introduction Statins are at the forefront of strategies to manage dyslipidemia, although they
are not always well tolerated. At 6–7 months after the drug was supplied, discontinuation …

Policosanol (PC) is a mixture of high molecular weight aliphatic primary alcohols. Currently,
a number of dietary supplements containing PC are commercially available in the US …

Study Objective. To compare the efficacy and safety of plant sterols and stanols as well as
policosanol in the treatment of coronary heart disease, as measured by a reduction in low …

Metabolic syndrome (MetS) is a set of cardiovascular risk factors which severely increases
the risk of type II diabetes, renal disease and cardiovascular disease. Over the last decades …

Policosanols are a mixture of aliphatic alcohols derived from purified sugar cane. When
administered at 5 to 20 mg/day, policosanols have been shown to decrease the risk of …

Brown adipose tissue (BAT) is an attractive therapeutic target for treating obesity and
metabolic diseases. Octacosanol is the main component of policosanol, a mixture of very …