PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application

Y Su, B Zhang, R Sun, W Liu, Q Zhu, X Zhang… - Drug …, 2021 - Taylor & Francis
Biodegradable microspheres have been widely used in the field of medicine due to their
ability to deliver drug molecules of various properties through multiple pathways and their …

Recent advances and applications of microspheres and nanoparticles in transarterial chemoembolization for hepatocellular carcinoma

G Jia, J Van Valkenburgh, AZ Chen… - Wiley …, 2022 - Wiley Online Library
Transarterial chemoembolization (TACE) is a recommended treatment for patients suffering
from intermediate and advanced hepatocellular carcinoma (HCC). As compared to the …

Designing natural polymer-based capsules and spheres for biomedical applications—a review

K Sharma, Z Porat, A Gedanken - Polymers, 2021 - mdpi.com
Natural polymers, such as polysaccharides and polypeptides, are potential candidates to
serve as carriers of biomedical cargo. Natural polymer-based carriers, having a core–shell …

Structure‐functions relationship of modified starches for pharmaceutical and biomedical applications

MA Labelle, P Ispas‐Szabo, MA Mateescu - Starch‐Stärke, 2020 - Wiley Online Library
Modified starch is widely used in pharmaceutical and biomedical sciences. Various
modifications such as functionalization, reorganization of the structure, or depolymerization …

Synthesis and assessment of sodium alginate-modified silk fibroin microspheres as potential hepatic arterial embolization agent

G Chen, R Wei, X Huang, F Wang, Z Chen - International journal of …, 2020 - Elsevier
Transcatheter arterial chemoembolization (TACE) is well known as an effective treatment for
hepatocellular carcinoma (HCC). In the present study, a novel embolic agent of sodium …

Anionic and ampholytic high-amylose starch derivatives as excipients for pharmaceutical and biopharmaceutical applications: structure-properties correlations

MA Labelle, P Ispas-Szabo, S Tajer, Y Xiao, B Barbeau… - Pharmaceutics, 2023 - mdpi.com
Many chemical modifications of starch are realized in organic (mostly methanol) phase,
allowing high degrees of substitution (DS). Some of these materials are used as …

Size-tunable and biodegradable thrombin-functionalized carboxymethyl chitin microspheres for endovascular embolization

F Leng, S Lei, B Luo, S Lv, L Huang, X Jiang - Carbohydrate Polymers, 2022 - Elsevier
As a minimally invasive method, endovascular embolization has been an effective strategy
for controlling bleeding and tumor treatment. Herein, carboxymethyl chitin embolic …

Biodegradable Microembolics with Nanografted Polyanions Enable High-Efficiency Drug Loading and Sustained Deep-Tumor Drug Penetration for Locoregional …

Y Ma, Z Li, Y Luo, Y Chen, L Ma, X Liu, J Xiao… - ACS …, 2024 - ACS Publications
Transarterial chemoembolization (TACE), the mainstay treatment of unresectable primary
liver cancer that primarily employs nondegradable drug-loaded embolic agents to achieve …

A biodegradable multifunctional porous microsphere composed of carrageenan for promoting imageable trans-arterial chemoembolization

L Kunliang, J Zhicheng, H Xiaolong, Y Dan, Z Yu… - International journal of …, 2020 - Elsevier
Trans-arterial chemoembolization (TACE) has been a mainstream treatment for
hepatocellular carcinoma (HCC), accordingly there are more requirements for embolic …

Engineered therapeutic proteins for sustained-release drug delivery systems

TTK Nguyen, KY Pham, S Yook - Acta Biomaterialia, 2023 - Elsevier
Proteins play a vital role in diverse biological processes in the human body, and protein
therapeutics have been applied to treat different diseases such as cancers, genetic …