Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …
disease caused by tobacco smoking in genetically susceptible individuals has been …
Club cell secretory protein in lung disease: emerging concepts and potential therapeutics
Club cell secretory protein (CCSP), also known as secretoglobin 1A1 (gene name
SCGB1A1), is one of the most abundant proteins in the lung, primarily produced by club …
SCGB1A1), is one of the most abundant proteins in the lung, primarily produced by club …
Lung hyperpermeability and asthma prevalence in schoolchildren: unexpected associations with the attendance at indoor chlorinated swimming pools
Aims: To study whether exposure to nitrogen trichloride in indoor chlorinated pools may
affect the respiratory epithelium of children and increase the risk of some lung diseases such …
affect the respiratory epithelium of children and increase the risk of some lung diseases such …
Oxidative DNA damage and inflammatory responses in cultured human cells and in humans exposed to traffic-related particles
U Vattanasit, P Navasumrit, MB Khadka… - International journal of …, 2014 - Elsevier
Particulate pollution is a major public health concern because epidemiological studies have
demonstrated that exposure to particles is associated with respiratory diseases and lung …
demonstrated that exposure to particles is associated with respiratory diseases and lung …
Exposure to ultrafine particles from ambient air and oxidative stress–induced DNA damage
EV Bräuner, L Forchhammer, P Møller… - Environmental …, 2007 - ehp.niehs.nih.gov
Background Particulate matter, especially ultrafine particles (UFPs), may cause health
effects through generation of oxidative stress, with resulting damage to DNA and other …
effects through generation of oxidative stress, with resulting damage to DNA and other …
Differences in plasma and sputum biomarkers between COPD and COPD–asthma overlap
H Iwamoto, J Gao, J Koskela, V Kinnula… - European …, 2014 - Eur Respiratory Soc
The pathophysiological features of chronic obstructive pulmonary disease (COPD)–asthma
overlap are poorly understood and there has been no study of plasma or sputum biomarkers …
overlap are poorly understood and there has been no study of plasma or sputum biomarkers …
[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease
GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …
immunity. The proteins are host defense lectins, belonging to the collectin family which also …
A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects
JS Lakind, ST Holgate, DR Ownby, AH Mansur… - Biomarkers, 2007 - Taylor & Francis
Biomarkers associated with asthma aetiology and exacerbation have been sought to shed
light on this multifactorial disease. One candidate is the serum concentration of the Clara cell …
light on this multifactorial disease. One candidate is the serum concentration of the Clara cell …
Infant swimming practice, pulmonary epithelium integrity, and the risk of allergic and respiratory diseases later in childhood
A Bernard, S Carbonnelle, X Dumont… - Pediatrics, 2007 - publications.aap.org
OBJECTIVE. Irritant gases and aerosols contaminating the air of indoor swimming pools can
affect the lung epithelium and increase asthma risk in children. We evaluated the impact of …
affect the lung epithelium and increase asthma risk in children. We evaluated the impact of …
Circulating surfactant protein D as a potential lung-specific biomarker of health outcomes in COPD: a pilot study
Background There is a paucity of surrogate lung-specific biological markers that can be
used to track disease progression and predict clinical outcomes in chronic obstructive …
used to track disease progression and predict clinical outcomes in chronic obstructive …