The field of medical ultrasound has undergone a significant evolution since the development
of microbubbles as contrast agents. However, because of their size, microbubbles remain in …

Nanomedicine in oncology has not had the success in clinical impact that was anticipated in
the early stages of the field's development. Ideally, nanomedicines selectively accumulate in …

Understanding the pressure dependence of the nonlinear behavior of ultrasonically excited
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …

Nanoscale ultrasound contrast agents, or nanobubbles, are being explored in preclinical
applications ranging from vascular and cardiac imaging to targeted drug delivery in cancer …

Lipid-shelled nanobubbles (NBs) are emerging as potential dual diagnostic and therapeutic
agents. Similar to their micron-scale counterparts, microbubbles (1–10 μm), they can act as …

Contrast-enhanced ultrasound with microbubbles has shown promise in detection of
prostate cancer (PCa), but sensitivity and specificity remain challenging. Targeted …

Ultrasound (US) is a widely used diagnostic imaging tool because it is inexpensive, safe,
portable, and broadly accessible. Ultrasound contrast agents (UCAs) are employed to …

Lipid shell-stabilized nanoparticles with a perfluorocarbon gas-core, or nanobubbles, have
recently attracted attention as a new contrast agent for molecular ultrasound imaging and …

This study explores the challenges associated with nanoparticle-based drug delivery to the
tumor parenchyma, focusing on the widely utilized enhanced permeability and retention …

Gas-core nanoscale bubbles (or nanobubbles) have gained significant recent attention as
promising contrast agents for cancer molecular imaging using medical ultrasound. Previous …