Mycobacterium marinum infection in fish and man: epidemiology, pathophysiology and management; a review

E Hashish, A Merwad, S Elgaml, A Amer… - Veterinary …, 2018 - Taylor & Francis
Mycobacterium marinum is an opportunistic pathogen inducing infection in fresh and marine
water fish. This pathogen causes necrotizing granuloma like tuberculosis, morbidity and …

Mycobacterium smegmatis: the vanguard of mycobacterial research

IL Sparks, KM Derbyshire, WR Jacobs Jr… - Journal of …, 2023 - Am Soc Microbiol
The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …

Immunity and immunopathology in the tuberculous granuloma

AJ Pagán, L Ramakrishnan - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Granulomas, organized aggregates of immune cells, are a defining feature of tuberculosis
(TB). Granuloma formation is implicated in the pathogenesis of a variety of inflammatory …

M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival

P Ge, Z Lei, Y Yu, Z Lu, L Qiang, Q Chai, Y Zhang… - Autophagy, 2022 - Taylor & Francis
The eukaryotic-type protein kinase G (PknG), one of the eleven eukaryotic type serine-
threonine protein kinase (STPK) in Mycobacterium tuberculosis (Mtb), is involved in …

The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

KE Zulauf, JT Sullivan, M Braunstein - PLoS pathogens, 2018 - journals.plos.org
To subvert host defenses, Mycobacterium tuberculosis (Mtb) avoids being delivered to
degradative phagolysosomes in macrophages by arresting the normal host process of …

Host Cell Targets of Released Lipid and Secreted Protein Effectors of Mycobacterium tuberculosis

J Augenstreich, V Briken - Frontiers in cellular and infection …, 2020 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is a very successful pathogen, strictly adapted to humans
and the cause of tuberculosis. Its success is associated with its ability to inhibit host cell …

Mycobacteriosis and infections with non-tuberculous mycobacteria in aquatic organisms: A review

MR Delghandi, M El-Matbouli, S Menanteau-Ledouble - Microorganisms, 2020 - mdpi.com
The Mycobacteriaceae constitute a family of varied Gram-positive organisms that include a
large number of pathogenic bacteria. Among these, non-tuberculous mycobacteria are …

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis

B Rieck, G Degiacomi, M Zimmermann… - PLoS …, 2017 - journals.plos.org
Sensing and response to changes in nutrient availability are essential for the lifestyle of
environmental and pathogenic bacteria. Serine/threonine protein kinase G (PknG) is …

A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development

KA Wolff, AH de la Peña, HT Nguyen, TH Pham… - PLoS …, 2015 - journals.plos.org
Survival of M. tuberculosis in host macrophages requires the eukaryotic-type protein kinase
G, PknG, but the underlying mechanism has remained unknown. Here, we show that PknG …

Release of mycobacterial antigens

L Majlessi, R Prados‐Rosales… - Immunological …, 2015 - Wiley Online Library
Mycobacterium tuberculosis has evolved from a Mycobacterium canettii‐like progenitor pool
into one of the most successful and widespread human pathogens. The pathogenicity of M …