Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2
2016-08-31 Assigned to BUCK INSTITUTE FOR RESEARCH ON AGING reassignment
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells
2017-03-14 Assigned to BUCK INSTITUTE FOR RESEARCH ON AGING reassignment
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
Treatment of ophthalmic conditions by selectively removing senescent cells from the eye
RM Laberge, J Campisi, M Demaria, N David… - US Patent …, 2018 - Google Patents
2018-01-29 Assigned to BUCK INSTITUTE FOR RESEARCH ON AGING reassignment
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease
RM Laberge, J Campisi, M Demaria, N David… - US Patent …, 2018 - Google Patents
2017-09-01 Assigned to BUCK INSTITUTE FOR RESEARCH ON AGING reassignment
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population
RM Laberge, J Campisi, A Davalos… - US Patent …, 2019 - Google Patents
2017-03-16 Assigned to MAYO FOUNDATION FOR MEDICAL EDUCATION AND
RESEARCH reassignment MAYO FOUNDATION FOR MEDICAL EDUCATION AND …
RESEARCH reassignment MAYO FOUNDATION FOR MEDICAL EDUCATION AND …
Bcl-2/Bcl-xL inhibitors and therapeutic methods using the same
S Wang, J Chen, D McEachern, L Bai, L Liu… - US Patent …, 2016 - Google Patents
The present invention is directed to inhibitors of Bcl-2/Bcl XL, to compositions comprising the
inhibitors, and to meth ods of using the inhibitors in a therapeutic treatment of con ditions …
inhibitors, and to meth ods of using the inhibitors in a therapeutic treatment of con ditions …
Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline
2017-04-11 Assigned to BUCK INSTITUTE FOR RESEARCH ON AGING reassignment
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
BUCK INSTITUTE FOR RESEARCH ON AGING ASSIGNMENT OF ASSIGNORS INTEREST …
Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques
Foamy macrophages with senescence markers accumulate in the subendothelial space at
the onset of atherosclerosis where they drive pathology by increasing expression of key …
the onset of atherosclerosis where they drive pathology by increasing expression of key …
Pd-1/pd-l1 inhibitors
E Aktoudianakis, A Cho, Z Du, M Graupe… - US Patent …, 2020 - Google Patents
2019-02-21 Assigned to GILEAD SCIENCES, INC. reassignment GILEAD SCIENCES, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye
RM Laberge, J Campisi, M Demaria, N David… - US Patent …, 2019 - Google Patents
Methods are provided herein for selectively killing senescent cells and for treating
senescence-associated diseases and disorders by administering a senolytic agent …
senescence-associated diseases and disorders by administering a senolytic agent …