Background Increasing evidence supports the association between hyperuricemia and
incident chronic kidney disease (CKD); however, there are conflicting data regarding the …

Accumulating evidence indicates that asymptomatic hyperuricemia is involved in the
development of hypertension and chronic kidney disease. A 2-hit model has been proposed …

Gout is an inflammatory disease manifested by the deposition of monosodium urate (MSU)
crystals in joints, cartilage, synovial bursa, tendons or soft tissues. Gout is not a new disease …

Background Chronic kidney disease (CKD) and hyperuricemia often coexist, and both
conditions are increasing in prevalence in the United States. However, their shared role in …

Background Chronic kidney disease (CKD) and hepatitis C virus (HCV) infection are closely
linked and both increase patient mortality. The association of HCV and risk of developing …

The function of uric acid (UA) in the genesis and evolution of chronic kidney disease (CKD)
has motivated numerous studies, but the results remain inconclusive. We sought to conduct …

Objective Evidence suggests that both serum uric acid (SUA) and high-density lipoprotein
cholesterol (HDL-C) are risk factors for chronic kidney disease (CKD). The SUA-to-HDL-C …

Epidemiological studies show that hyperuricemia independently predicts the development of
chronic kidney disease (CKD) in individuals with normal kidney function both in the general …

Background Studies have shown inconsistent results about the association between serum
uric acid levels and mortality in patients with chronic kidney disease (CKD). Methods A …

Hyperuricemia (HU) is common in patients with chronic kidney disease (CKD), and
accumulating evidence suggests it has a pathogenic role in the progression of the disease …