Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …

Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Fibrotic skin disease represents a major global healthcare burden, characterized by
fibroblast hyperproliferation and excessive accumulation of extracellular matrix. Fibroblasts …

Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …

Tendons mainly function as load‐bearing tissues in the muscloskeletal system; transmitting
loads from muscle to bone. Tendons are dynamic structures that respond to the magnitude …

Abstract The transcription factor Mohawk (Mkx) is expressed in developing tendons and is
an important regulator of tenogenic differentiation. However, the exact roles of Mkx in …

The earthworm is particularly fascinating to biologists because of its strong regenerative
capacity. However, many aspects of its regeneration in nature remain elusive. Here we …

Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …

Tendon injuries are a common cause of physical disability. They present a clinical challenge
to orthopedic surgeons because injured tendons respond poorly to current treatments …

The tendon/ligament-to-bone transition (enthesis) is a highly specialized interphase tissue
with structural gradients of extracellular matrix composition, collagen molecule alignment …