Sensitization to fungi and long term or uncontrolled fungal infection are associated with poor
control of asthma, the likelihood of more severe disease and complications such as …

Despite seasonal vaccines, influenza-related hospitalization and death rates have remained
unchanged over the past 5 years. Influenza pathogenesis has 2 crucial clinical components; …

Background Inhaled corticosteroids are important in the management of chronic obstructive
pulmonary disease (COPD), but can slightly increase the risk of pneumonia in patients with …

Extracellular vesicles are produced by many pathogenic microorganisms and have varied
functions that include secretion and release of microbial factors, which contribute to …

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity
and mortality worldwide. In the lower airways of COPD patients, bacterial infection is a …

Prevention of infectious diseases through immunisation of the growing ageing adult
population is essential to improve healthy ageing. However, many licenced and …

Vi capsular polysaccharide, a linear homopolymer of α-1, 4-linked N-
acetylgalactosaminuronate, is characteristically produced by Salmonella enterica serovar …

Background Both aging and obesity are related to dysregulated immune function, which may
be responsible for increased risk of infection and also chronic non-infectious diseases …

Infections by opportunistic bacteria have significant contributions to morbidity and mortality
of hospitalized patients and also lead to high expenses in healthcare. In this setting, one of …

Age is associated with reduced efficacy of vaccines and linked to higher risk of severe
COVID-19. Here we determined the impact of ageing on the efficacy of a SARS-CoV-2 …