The transcription factor NF-E2 p45-related factor 2 (Nrf2; gene name NFE2L2) allows
adaptation and survival under conditions of stress by regulating the gene expression of …

Mitochondria play essential roles in cellular bioenergetics, biosynthesis, and apoptosis.
During the process of respiration and oxidative phosphorylation, mitochondria utilize oxygen …

Autism spectrum disorder (ASD), characterized by both impaired communication and social
interaction, and by stereotypic behavior, affects about 1 in 68, predominantly males. The …

Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …

Recently, there has been an increasing amount of literature published on the effects of 4-
phenylbutyric acid (4-PBA) in various biological systems. 4-PBA is currently used clinically to …

The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms
against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing …

DNA replication is a highly demanding process regarding the energy and material supply
and must be precisely regulated, involving multiple cellular feedbacks. The slowing down or …

Abstract Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental
disorders with no drugs treating the core symptoms and no validated biomarkers for clinical …

Drug resistance remains a barrier in the clinical treatment of ovarian cancer. Proteasomal
and antioxidant activities play important roles in tumor drug resistance, and increasing …

Autism spectrum disorders (ASD) are a family of complex neurodevelopmental disorders,
characterized mainly through deficits in social behavior and communication. While the …