Epigenetic signatures underlying inflammation: An interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized nutrition

O Ramos-Lopez, FI Milagro, JI Riezu-Boj… - Inflammation …, 2021 - Springer
Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Guide for current nutrigenetic, nutrigenomic, and nutriepigenetic approaches for precision nutrition involving the prevention and management of chronic diseases …

O Ramos-Lopez, FI Milagro, H Allayee… - Lifestyle …, 2017 - karger.com
Chronic diseases, including obesity, are major causes of morbidity and mortality in most
countries. The adverse impacts of obesity and associated comorbidities on health remain a …

DNA hypomethylation and its mediation in the effects of fine particulate air pollution on cardiovascular biomarkers: a randomized crossover trial

R Chen, X Meng, A Zhao, C Wang, C Yang, H Li… - Environment …, 2016 - Elsevier
Background Short-term exposure to fine particulate matter (PM 2.5) air pollution has been
associated with altered DNA methylation in observational studies, but it remains unclear …

DNA methylation and hydroxymethylation levels in relation to two weight loss strategies: energy-restricted diet or bariatric surgery

CF Nicoletti, CB Nonino, BAP de Oliveira, MAS Pinhel… - Obesity surgery, 2016 - Springer
Background Weight loss can be influenced by genetic factors and epigenetic mechanisms
that participate in the regulation of body weight. This study aimed to investigate whether the …

Childhood trauma, the stress response and metabolic syndrome: a focus on DNA methylation

JS Womersley, J Nothling, S Toikumo… - European Journal of …, 2022 - Wiley Online Library
Childhood trauma (CT) is well established as a potent risk factor for the development of
mental disorders. However, the potential of adverse early experiences to exert chronic and …

GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β‐catenin and ALK5/SMAD2/3 pathways

J Frohlich, K Kovacovicova, M Raffaele… - Cell …, 2022 - Wiley Online Library
Objective GDF11 is a member of the TGF‐β superfamily that was recently implicated as
potential “rejuvenating” factor, which can ameliorate metabolic disorders. The main objective …

The embryonic stress response to in vitro culture: insight from genomic analysis

G Cagnone, MA Sirard - Reproduction, 2016 - rep.bioscientifica.com
Recent genomic studies have shed light on the impact of in vitro culture (IVC) on embryonic
homeostasis and the differential gene expression profiles associated with lower …

Epigenetic modification by dietary factors: Implications in metabolic syndrome

JH Park, SH Kim, MS Lee, MS Kim - Molecular aspects of medicine, 2017 - Elsevier
Dietary factors play a role in normal biological processes and are involved in the regulation
of pathological progression over a lifetime. Evidence has emerged indicating that dietary …

Effects of short‐and long‐term Mediterranean‐based dietary treatment on plasma LC‐QTOF/MS metabolic profiling of subjects with metabolic syndrome features: The …

I Bondia‐Pons, JA Martinez… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope Adherence to the Mediterranean diet has been associated with a reduced risk of
metabolic syndrome (MetS). Metabolomics approach may contribute to identify beneficial …

SERPINE1 and its co-expressed genes are associated with the progression of clear cell renal cell carcinoma

L Guo, T An, Z Wan, Z Huang, T Chong - BMC urology, 2023 - Springer
Background Clear cell renal cell carcinoma (ccRCC) is a frequently occurring malignant
tumor of the urinary system. Despite extensive research, the regulatory mechanisms …