Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

Infections caused by protozoan parasites burden the world with huge costs in terms of
human and animal health. Most parasitic diseases caused by protozoans are neglected …

The presence of the endogenous Leishmania RNA virus 1 (LRV1) replicating stably within
some parasite species has been associated with the development of more severe forms of …

Cutaneous leishmaniasis has various outcomes, ranging from self-healing reddened
papules to extensive open ulcerations that metastasise to secondary sites and are often …

Leishmania parasites preferentially invade macrophages, the professional phagocytic cells,
at the site of infection. Macrophages play conflicting roles in Leishmania infection either by …

The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1) has been
implicated as a pathogenicity factor for leishmaniasis in rodent models and human disease …

Leishmaniasis is a vector-borne infectious disease caused by different species of protozoa
from the Leishmania genus. Classically, the disease can be classified into two main clinical …

Objective Leishmaniasis is caused by different Leishmania spp. Treatment failure (TF) of
cutaneous leishmaniasis (CL) is a serious issue that may be due to various reasons …

The various symptomatic outcomes of cutaneous leishmaniasis relates to the type and
potency of its underlying inflammatory responses. Presence of the cytoplasmic Leishmania …

A relevant aspect in the epidemiology of Tegumentary Leishmaniasis (TL) are the
Leishmania parasites carrying a viral endosymbiont, Leishmania RNA Virus 1 (LRV1), a …