Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis

J Jeffery, D Sinha, S Srihari, M Kalimutho, KK Khanna - Oncogene, 2016 - nature.com
CEP55 was initially identified as a pivotal component of abscission, the final stage of
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …

Oncobiology and treatment of breast cancer in young women

R Kumar, C Abreu, M Toi, S Saini, S Casimiro… - Cancer and Metastasis …, 2022 - Springer
Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …

Deep learning-based breast cancer grading and survival analysis on whole-slide histopathology images

SC Wetstein, VMT de Jong, N Stathonikos, M Opdam… - Scientific reports, 2022 - nature.com
Breast cancer tumor grade is strongly associated with patient survival. In current clinical
practice, pathologists assign tumor grade after visual analysis of tissue specimens …

FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC

H Chi, X Gao, Z Xia, W Yu, X Yin, Y Pan… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Endometrial cancer (UCEC) is a highly heterogeneous gynecologic
malignancy that exhibits variable prognostic outcomes and responses to immunotherapy …

Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures

Z Kan, Y Ding, J Kim, HH Jung, W Chung, S Lal… - Nature …, 2018 - nature.com
Breast cancer (BC) in the Asia Pacific regions is enriched in younger patients and rapidly
rising in incidence yet its molecular bases remain poorly characterized. Here we analyze the …

Cancer progression is mediated by proline catabolism in non-small cell lung cancer

Y Liu, C Mao, M Wang, N Liu, L Ouyang, S Liu, H Tang… - Oncogene, 2020 - nature.com
Dysregulated metabolism contributes to cancer initiation and progression, but the key
drivers of these pathways are just being discovered. Here, we report a critical role for proline …

The prognostic impact of age in different molecular subtypes of breast cancer

C Liedtke, A Rody, O Gluz, K Baumann, D Beyer… - Breast cancer research …, 2015 - Springer
Breast cancer is a heterogeneous entity composed of distinct molecular subgroups with
different molecular and clinical features. We analyzed the association between molecular …

UBE2T promotes hepatocellular carcinoma cell growth via ubiquitination of p53

L Liu, M Yang, Q Peng, M Li, Y Zhang, Y Guo… - Biochemical and …, 2017 - Elsevier
Deregulation of Ubiquitin-conjugating enzyme E2T (UBE2T) contributes to the progression
of human cancers. However, its clinical significance and role in hepatocellular carcinoma …

Comprehensive genomic profiling of inflammatory breast cancer cases reveals a high frequency of clinically relevant genomic alterations

JS Ross, SM Ali, K Wang, D Khaira, NA Palma… - Breast cancer research …, 2015 - Springer
Inflammatory breast cancer (IBC) is a distinct clinicopathologic entity that carries a worse
prognosis relative to non-IBC breast cancer even when matched for standard biomarkers …

Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis

Z Wang, D Katsaros, Y Shen, Y Fu, EM Canuto… - PloS one, 2015 - journals.plos.org
To investigate the biologic relevance and clinical implication of genes involved in multiple
gene expression signatures for breast cancer prognosis, we identified 16 published gene …