H Miller, Z Zhou, J Shepherd… - Reports on Progress …, 2017 - iopscience.iop.org
Single-molecule biophysics has transformed our understanding of biology, but also of the physics of life. More exotic than simple soft matter, biomatter lives far from thermal …
Intercalation of drug molecules into synthetic DNA nanostructures formed through self- assembled origami has been postulated as a valuable future method for targeted drug …
Staphylococcus aureus is an important pathogen, giving rise to antimicrobial resistance in cell strains such as Methicillin Resistant S. aureus (MRSA). Here we report an image …
High-speed single-molecule fluorescence microscopy in vivo shows that transcription factors in eukaryotes can act in oligomeric clusters mediated by molecular crowding and …
S Shashkova, MC Leake - Current Opinion in Systems Biology, 2018 - Elsevier
How does the interplay between biomolecules result in the emergence of cellular complexity at higher length scales? This interplay in even simple biological processes is often too …
This thesis describes the design, construction and application of a novel magneto-optical tweezers with super-resolution fluorescence microscopy for manipulation, force/torque …
Fluorescence microscopy is an invaluable tool in the biosciences, a genuine workhorse technique offering exceptional contrast in conjunction with high specificity of labelling with …
Staphylococcus aureus is a coccal bacterium, which divides by binary fission. After division the cells remain attached giving rise to small clusters, with a characteristic'bunch of grapes' …