Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

Synthetic immunology, the development of synthetic systems capable of modulating and/or
manipulating immunological functions, represents an emerging field of research with …

The regulatory functions of Siglecs (sialic acid binding immunoglobulin-like lectins) in the
immune system provide opportunities for innovative therapeutic strategies for a wide range …

Stacking interactions in nitroarene binding sites of proteins were studied through analyses of
structures in the protein data bank (PDB), as well as DFT and ab initio computations applied …

AhR Aryl hydrocarbon receptor AICD Activation-induced cell death ALIS Aggresome-like
structure APC Antigen-presenting cell AR Autosomal recessive ASGPR Asialoglycoprotein …

Techniques eliciting anti-tumor immunity are of interest for immunotherapy. We herein report
the covalent incorporation of a non-self immunogen into the tumor glycocalyx by metabolic …

Naturally occurring glycans are often found in a multivalent presentation. Cell surface
receptors that recognize these displays may form clusters, which can lead to signalling or …

Inhibition of AB5-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs)
that mediate assembly of supramolecular complexes involving the toxin's pentameric cell …

The ability to harness one's endogenous immune response against a pathogen has
significantly advanced the treatment of many serious diseases. While immune-based …

Polymers have been used for a long time in biomedical fields such as drug delivery or tissue
regeneration. However, their use as therapeutic agents by themselves is relatively recent. 1 …