G Curia, C Lucchi, J Vinet, F Gualtieri… - Current medicinal …, 2014 - ingentaconnect.com
Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly caused by a primary brain injury that occurred a long time before the appearance of …
В руководстве представлены результаты 60-летней работы автора в области детской и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …
C Lentini, M d'Orange, N Marichal, MM Trottmann… - Cell stem cell, 2021 - cell.com
Reprogramming brain-resident glial cells into clinically relevant induced neurons (iNs) is an emerging strategy toward replacing lost neurons and restoring lost brain functions. A …
Epileptic seizures are characterized by periods of hypersynchronous, hyperexcitability within brain networks. Most seizures involve two stages: an initial tonic phase, followed by a longer …
F Wendling, A Hernandez, JJ Bellanger… - Journal of Clinical …, 2005 - journals.lww.com
In human partial epilepsies and in experimental models of chronic and/or acute epilepsy, the role of inhibition and the relationship between the inhibition and excitation and …
A Ludányi, L Erőss, S Czirják, J Vajda… - Journal of …, 2008 - Soc Neuroscience
Endocannabinoid signaling is a key regulator of synaptic neurotransmission throughout the brain. Compelling evidence shows that its perturbation leads to development of epileptic …
L Yekhlef, GL Breschi, L Lagostena… - Journal of …, 2015 - journals.physiology.org
GABAergic interneurons are thought to play a critical role in eliciting interictal spikes (IICs) and triggering ictal discharges in temporal lobe epilepsy, yet the contribution of different …
Z Maglóczky, TF Freund - Trends in neurosciences, 2005 - cell.com
This review focuses on the epileptic human temporal lobe, primarily on recent findings related to changes in hippocampal GABAergic interneuron circuits that have a central role in …
Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an essential role in regulating many physiological processes, such as intracellular signaling …