Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology

A Niarakis, D Waltemath, J Glazier… - Briefings in …, 2022 - academic.oup.com
Computational models are often employed in systems biology to study the dynamic
behaviours of complex systems. With the rise in the number of computational models, finding …

Specifications of standards in systems and synthetic biology: status and developments in 2022 and the COMBINE meeting 2022

M König, P Gleeson, M Golebiewski… - Journal of Integrative …, 2023 - degruyter.com
This special issue of the Journal of Integrative Bioinformatics contains updated
specifications of COMBINE standards in systems and synthetic biology. The 2022 special …

Specifications of standards in systems and synthetic biology: status, developments, and tools in 2024

M Golebiewski, G Bader, P Gleeson… - Journal of Integrative …, 2024 - degruyter.com
The “COmputational Modeling in BIology NEtwork”(COMBINE) initiative aims to harmonise
the development of diverse community standards for computational models in biology [1, 2] …

StonPy: a tool to parse and query collections of SBGN maps in a graph database

A Rougny, I Balaur, A Luna, A Mazein - Bioinformatics, 2023 - academic.oup.com
The systems biology graphical notation (SBGN) has become the de facto standard for the
graphical representation of molecular maps. Having rapid and easy access to the content of …

Specifications of standards in systems and synthetic biology: status and developments in 2020

F Schreiber, B Sommer, T Czauderna… - Journal of integrative …, 2020 - degruyter.com
Specifications of standards in systems and synthetic biology: status and developments in 2020
Skip to content Should you have institutional access? Here's how to get it ... De Gruyter € EUR …

Specifications of standards in systems and synthetic biology

F Schreiber, GD Bader, M Golebiewski… - Journal of integrative …, 2015 - degruyter.com
Standards shape our everyday life. From nuts and bolts to electronic devices and
technological processes, standardised products and processes are all around us. Standards …

STON: exploring biological pathways using the SBGN standard and graph databases

V Touré, A Mazein, D Waltemath, I Balaur, M Saqi… - BMC …, 2016 - Springer
Abstract Background When modeling in Systems Biology and Systems Medicine, the data is
often extensive, complex and heterogeneous. Graphs are a natural way of representing …

Metabolomics, standards, and metabolic modeling for synthetic biology in plants

CB Hill, T Czauderna, M Klapperstück… - … in bioengineering and …, 2015 - frontiersin.org
Life on earth depends on dynamic chemical transformations that enable cellular functions,
including electron transfer reactions, as well as synthesis and degradation of biomolecules …

A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation

A Rougny, L Paulevé, M Teboul, F Delaunay - BMC bioinformatics, 2021 - Springer
Background The temporal coordination of biological processes by the circadian clock is an
important mechanism, and its disruption has negative health outcomes, including cancer …

VANTED: a tool for integrative visualization and analysis of-omics data

A Hartmann, AM Jozefowicz - Plant Membrane Proteomics: Methods and …, 2018 - Springer
The investigation of biological systems from different perspectives leads, due to novel-omics
technologies, to large-scale, heterogeneous, and complex datasets. To elucidate molecular …