Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer
Drug resistance in breast cancer cell populations has been shown to arise through
phenotypic transition of cancer cells to a drug-tolerant state, for example through epithelial …
phenotypic transition of cancer cells to a drug-tolerant state, for example through epithelial …
Morphodynamical cell state description via live-cell imaging trajectory embedding
Time-lapse imaging is a powerful approach to gain insight into the dynamic responses of
cells, but the quantitative analysis of morphological changes over time remains challenging …
cells, but the quantitative analysis of morphological changes over time remains challenging …
Cyclic control equilibria for switched systems with applications to ecological systems
AL Anderson, P Abuin, A Ferramosca… - … Journal of Robust …, 2023 - Wiley Online Library
The main contribution of this article is to provide the key concept—from a control point of
view—of a region of the state space called cyclic control equilibria, which is a permanence …
view—of a region of the state space called cyclic control equilibria, which is a permanence …
Discrete-time MPC for switched systems with applications to biomedical problems
This paper studies switched systems in which the manipulated control action is the time-
depending switching signal. To control the switched systems means to select an …
depending switching signal. To control the switched systems means to select an …
Permanence regions for switched linear systems under waiting-time constraints
When switched systems are restricted by waiting-time constraints, some basic concepts such
as equilibria, stability regions and invariant regions need to be updated. In this work, we …
as equilibria, stability regions and invariant regions need to be updated. In this work, we …
Discrete-time switching MPC with applications to mitigate resistance in viral infections
Many engineering applications can be described as switched linear systems, in which the
manipulated control action is the time-dependent switching signal. In such a case, the …
manipulated control action is the time-dependent switching signal. In such a case, the …
Morphodynamical cell-state description via live-cell imaging trajectory embedding
J Copperman, SM Gross, YH Chang, LM Heiser… - Biophysical …, 2022 - cell.com
Time-lapse imaging provides powerful insight into the dynamical response of cells to
perturbation, but the quantitative analysis of morphological changes over time is a …
perturbation, but the quantitative analysis of morphological changes over time is a …
Identification of Cancer Cell Population Dynamics Leveraging the Effect of Pre-Treatment for Drug Schedule Design
M Wiggert, M Turnidge, Z Cohen… - 2021 American …, 2021 - ieeexplore.ieee.org
Sequences of different drugs have shown potential to improve treatment strategies for
cancer. Typical switched system approaches model the population dynamics of each drug …
cancer. Typical switched system approaches model the population dynamics of each drug …
[PDF][PDF] Data-Driven Identification of Cancer Cell Population Dynamics Leveraging the Effect of Pre-Treatment for Drug Schedule Design
Sequences of different drugs have shown potential to improve treatment strategies for
cancer. Typical switched system approaches model the population dynamics of each drug …
cancer. Typical switched system approaches model the population dynamics of each drug …
[引用][C] Perbandingan Optimasi Penjadwalan Pemberian Obat Kanker Menggunakan Greedy Algorithm Dan Firefly Algorithm
N Evawani, AG Putrada, M Abdurohman - eProceedings of Engineering, 2020