Regulated relocalization of signaling and trafficking proteins is crucial for the control of many
cellular processes and is driven by a series of domains that respond to alterations at …

Mammalian and bacterial cells sense and exert mechanical forces through the process of
mechanotransduction, which interconverts biochemical and physical signals. This is …

The quantification of membrane-associated biomolecular interactions is crucial to our
understanding of various cellular processes. State-of-the-art single-molecule approaches …

Assembly of highly curved membrane structures is essential to cellular physiology. The
prevailing view has been that proteins with curvature-promoting structural motifs, such as …

The ESCRT-III membrane fission machinery maintains the integrity of the nuclear envelope.
Although primary nuclei resealing takes minutes, micronuclear envelope ruptures seem to …

KRas is a major proto-oncogene product whose signaling activity depends on its level of
enrichment on the plasma membrane (PM). This PM localization relies on posttranslational …

Arabidopsis thaliana respiratory burst oxidase homolog D (RbohD) functions as an essential
regulator of reactive oxygen species (ROS). However, our understanding of the regulation of …

Biological membranes fulfill many important tasks within living organisms. In addition to
separating cellular volumes, membranes confine the space available to membrane …

The lipid-anchored small GTPase Ras is an important signaling node in mammalian cells. A
number of observations suggest that Ras is laterally organized within the cell membrane …

AB5 bacterial toxins and polyomaviruses induce membrane curvature as a mechanism to
facilitate their entry into host cells. How membrane bending is accomplished is not yet fully …