[HTML][HTML] Bioelectric signaling in regeneration: mechanisms of ionic controls of growth and form
KA McLaughlin, M Levin - Developmental biology, 2018 - Elsevier
The ability to control pattern formation is critical for the both the embryonic development of
complex structures as well as for the regeneration/repair of damaged or missing tissues and …
complex structures as well as for the regeneration/repair of damaged or missing tissues and …
MAPK/ERK pathway as a central regulator in vertebrate organ regeneration
X Wen, L Jiao, H Tan - International journal of molecular sciences, 2022 - mdpi.com
Damage to organs by trauma, infection, diseases, congenital defects, aging, and other
injuries causes organ malfunction and is life-threatening under serious conditions. Some of …
injuries causes organ malfunction and is life-threatening under serious conditions. Some of …
Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo
M Levin - Molecular biology of the cell, 2014 - Am Soc Cell Biol
In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
Molecular bioelectricity in developmental biology: new tools and recent discoveries: control of cell behavior and pattern formation by transmembrane potential …
M Levin - Bioessays, 2012 - Wiley Online Library
Significant progress in the molecular investigation of endogenous bioelectric signals during
pattern formation in growing tissues has been enabled by recently developed techniques …
pattern formation in growing tissues has been enabled by recently developed techniques …
Endogenous electric fields as guiding cue for cell migration
RHW Funk - Frontiers in physiology, 2015 - frontiersin.org
This review covers two topics:(1)“membrane potential of low magnitude and related electric
fields (bioelectricity)” and (2)“cell migration under the guiding cue of electric fields (EF).” …
fields (bioelectricity)” and (2)“cell migration under the guiding cue of electric fields (EF).” …
Regulation of cell behavior and tissue patterning by bioelectrical signals: challenges and opportunities for biomedical engineering
M Levin, CG Stevenson - Annual review of biomedical …, 2012 - annualreviews.org
Achieving control over cell behavior and pattern formation requires molecular-level
understanding of regulatory mechanisms. Alongside transcriptional networks and …
understanding of regulatory mechanisms. Alongside transcriptional networks and …
Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation
Alongside the well-known chemical modes of cell-cell communication, we find an important
and powerful system of bioelectrical signaling: changes in the resting voltage potential (V …
and powerful system of bioelectrical signaling: changes in the resting voltage potential (V …
Re-membering the body: applications of computational neuroscience to the top-down control of regeneration of limbs and other complex organs
A major goal of regenerative medicine and bioengineering is the regeneration of complex
organs, such as limbs, and the capability to create artificial constructs (so-called biobots) …
organs, such as limbs, and the capability to create artificial constructs (so-called biobots) …
Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities
M Levin - Wiley Interdisciplinary Reviews: Systems Biology and …, 2013 - Wiley Online Library
Transformative impact in regenerative medicine requires more than the reprogramming of
individual cells: advances in repair strategies for birth defects or injuries, tumor …
individual cells: advances in repair strategies for birth defects or injuries, tumor …