Dementia is one of the greatest global challenges for public health; however, the
relationship between anticholinergic drugs and dementia remains unclear. The aim of the …

Background the long-term effect of the use of drugs with anticholinergic activity on cognitive
function remains unclear. Methods we conducted a systematic review and meta-analysis of …

As the world's population ages, the incidence of Parkinson's disease (PD), the second most
common neurological ailment, keeps increasing. It is estimated that 1% of the global …

Background Medications with anticholinergic properties are commonly prescribed to older
adults. The cumulative anticholinergic effect of all the medications a person takes is referred …

The relative importance of antimuscarinic anticholinergic medications for Parkinson's
disease (PD) declined after the introduction of levodopa, such that anticholinergic …

Background Anticholinergic drugs are commonly prescribed, especially to older adults.
Anticholinergic burden scales (ABS) have been used to evaluate the cumulative effects of …

Introduction: Anticholinergic burden may be an important risk factor for the cognitive
impairment. Especially in polypharmacy, even drugs with low anticholinergic effects may …

Background Anticholinergic drugs are associated with significant cognitive and other
adverse events in older adults, including those with Parkinson's disease (PD) …

Introduction Anticholinergic medications are effective for a wide variety of indications, but are
associated with significant central adverse effects, especially cognitive decline and …

As the prevalence of Parkinson's disease (PD) grows, so too does the population at-risk of
developing PD, those in the so-called prodromal period. This period can span from those …