The killer pseudokinase mixed lineage kinase domain-like protein (MLKL)
JM Murphy - Cold Spring Harbor Perspectives in Biology, 2020 - cshperspectives.cshlp.org
Whereas the apoptosis cell death pathway typically enables cells to undergo death in an
immunologically silent manner, cell death by necroptosis induces cell lysis and release of …
immunologically silent manner, cell death by necroptosis induces cell lysis and release of …
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
EJ Petrie, RW Birkinshaw, A Koide… - Proceedings of the …, 2020 - National Acad Sciences
The necroptosis cell death pathway has been implicated in host defense and in the
pathology of inflammatory diseases. While phosphorylation of the necroptotic effector …
pathology of inflammatory diseases. While phosphorylation of the necroptotic effector …
MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF
The blockade of cellular differentiation represents a hallmark of acute myeloid leukemia
(AML), which is largely attributed to the dysfunction of lineage-specific transcription factors …
(AML), which is largely attributed to the dysfunction of lineage-specific transcription factors …