Medicinal plant-based drug delivery system for inflammatory bowel disease

N Li, M Wang, Z Lyu, K Shan, Z Chen, B Chen… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic recurrent intestinal disease. The incidence
rate of IBD is increasing year by year, which seriously endangers human health worldwide …

Review of konjac glucomannan structure, properties, gelation mechanism, and application in medical biology

Y Sun, X Xu, Q Zhang, D Zhang, X Xie, H Zhou, Z Wu… - Polymers, 2023 - mdpi.com
Konjac glucomannan (KGM) is a naturally occurring macromolecular polysaccharide that
exhibits remarkable film–forming and gel–forming properties, and a high degree of …

Prebiotic saccharides polymerization improves the encapsulation efficiency, stability, bioaccessibility and gut microbiota modulation of urolithin A liposomes

Y Hu, L Zhang, Q Wen, X Cheng, L Zhou… - International Journal of …, 2024 - Elsevier
This work was to investigate the effect of four prebiotic saccharides gum arabic (GA),
fructooligosaccharide (FOS), konjac glucomannan (KGM), and inulin (INU) incorporation on …

Nanoparticle-Based Drug Delivery Systems for Inflammatory Bowel Disease Treatment

J Gao, J Li, Z Luo, H Wang, Z Ma - Drug Design, Development and …, 2024 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory condition
characterized by recurring inflammation of the intestinal mucosa. However, the existing IBD …

Konjac glucomannan exerts regulatory effects on macrophages and its applications in biomedical engineering

X Pan, Q Zong, C Liu, H Wu, B Fu, Y Wang, W Sun… - Carbohydrate …, 2024 - Elsevier
Konjac glucomannan (KGM) molecular chains contain a small amount of acetyl groups and
a large number of hydroxyl groups, thereby exhibiting exceptional water retention and gel …

Applications of polysaccharides in enzyme-triggered oral colon-specific drug delivery systems: A review

T Gong, X Liu, X Wang, Y Lu, X Wang - International Journal of Biological …, 2024 - Elsevier
Enzyme-triggered oral colon-specific drug delivery system (EtOCDDS 1) can withstand the
harsh stomach and small intestine environments, releasing encapsulated drugs selectively …

Recognizing the biological barriers and pathophysiological characteristics of the gastrointestinal tract for the design and application of nanotherapeutics

S Li, T Wu, J Wu, W Chen, D Zhang - Drug Delivery, 2024 - Taylor & Francis
The gastrointestinal tract (GIT) is an important and complex system by which humans to
digest food and absorb nutrients. The GIT is vulnerable to diseases, which may led to …

Recent developments and new directions in the use of natural products for the treatment of inflammatory bowel disease

Y Feng, M Pan, R Li, W He, Y Chen, S Xu, H Chen… - Phytomedicine, 2024 - Elsevier
Background Inflammatory bowel disease (IBD) represents a significant global health
challenge, and there is an urgent need to explore novel therapeutic interventions. Natural …

Application of Polymers as Drug Nanocarriers in the Oral Treatment of Ulcerative Colitis

X Liu, L Huang, E Wu, Z Wei, J Wang… - ChemistrySelect, 2024 - Wiley Online Library
Ulcerative colitis (UC) is a chronic non‐specific inflammatory disease of the intestines with a
high prevalence. Polymer‐prepared nanoparticles are well‐targeted, highly biocompatible …

Relatório de Estágio-Centro de Potencial e Inovação de Recursos Naturais (IPGuarda) & Laboratório Nacional do Medicamento (Lisboa)

IA Pinto - 2023 - bdigital.ipg.pt
Os estágios curriculares apresentam-se como o primeiro contacto com a futura atividade
profissional dos alunos universitários e permitem não só aplicar os conhecimentos teóricos …