Acute kidney injury and maladaptive tubular repair leading t... : Current Opinion in Nephrology
and Hypertension Acute kidney injury and maladaptive tubular repair leading to renal fibrosis …

The most classical view of the renin-angiotensin system (RAS) emphasizes its role as an
endocrine regulator of sodium balance and blood pressure. However, it has long become …

Incomplete repair after acute kidney injury can lead to development of chronic kidney
disease. To define the mechanism of this response, we compared mice subjected to …

Acute kidney injury (AKI) is one of the main conditions responsible for chronic kidney
disease (CKD), including end-stage renal disease (ESRD) as a long-term complication …

Sepsis acute kidney injury (SAKI) is a common complication of sepsis, accounting for 26–
50% of all acute kidney injury (AKI). AKI is an independent risk factor for increased mortality …

Renal injury and the development of albuminuria are tightly connected with the loss of
podocytes. Podocyte damages cause proteinuric renal diseases since podocyte foot …

Store-operated Ca2+ entry (SOCE) is the major pathway of Ca2+ entry in mammalian cells,
and regulates a variety of cellular functions including proliferation, motility, apoptosis, and …

Tubular epithelial cells (TECs) represent the primary site of renal ischemia/reperfusion injury
(RIRI). However, whether the damage of TECs could drive the initiation of inflammation was …

Podocyte, the gatekeeper of the glomerular filtration barrier, is a primary target for growth
factor and Ca2+ signaling whose perturbation leads to proteinuria. However, the effects of …

Podocyte injury induced by hyperglycemia is the main cause of kidney dysfunction in
diabetic nephropathy. However, the underlying mechanism is unclear. Store-operated Ca 2+ …