[HTML][HTML] Hox genes and regional patterning of the vertebrate body plan

M Mallo, DM Wellik, J Deschamps - Developmental biology, 2010 - Elsevier
Several decades have passed since the discovery of Hox genes in the fruit fly Drosophila
melanogaster. Their unique ability to regulate morphologies along the anteroposterior (AP) …

Evolution of gene regulatory networks controlling body plan development

IS Peter, EH Davidson - Cell, 2011 - cell.com
Evolutionary change in animal morphology results from alteration of the functional
organization of the gene regulatory networks (GRNs) that control development of the body …

[HTML][HTML] Progressive loss of function in a limb enhancer during snake evolution

EZ Kvon, OK Kamneva, US Melo, I Barozzi… - Cell, 2016 - cell.com
The evolution of body shape is thought to be tightly coupled to changes in regulatory
sequences, but specific molecular events associated with major morphological transitions in …

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

FJ Vonk, NR Casewell, CV Henkel… - Proceedings of the …, 2013 - National Acad Sciences
Snakes are limbless predators, and many species use venom to help overpower relatively
large, agile prey. Snake venoms are complex protein mixtures encoded by several …

Conservation of transcription factor binding specificities across 600 million years of bilateria evolution

KR Nitta, A Jolma, Y Yin, E Morgunova, T Kivioja… - elife, 2015 - elifesciences.org
Divergent morphology of species has largely been ascribed to genetic differences in the
tissue-specific expression of proteins, which could be achieved by divergence in cis …

The Burmese python genome reveals the molecular basis for extreme adaptation in snakes

TA Castoe, APJ de Koning, KT Hall… - Proceedings of the …, 2013 - National Acad Sciences
Snakes possess many extreme morphological and physiological adaptations. Identification
of the molecular basis of these traits can provide novel understanding for vertebrate biology …

Megaevolutionary dynamics and the timing of evolutionary innovation in reptiles

TR Simões, O Vernygora, MW Caldwell… - Nature …, 2020 - nature.com
The origin of phenotypic diversity among higher clades is one of the most fundamental
topics in evolutionary biology. However, due to methodological challenges, few studies have …

Reassessing the role of Hox genes during vertebrate development and evolution

M Mallo - Trends in Genetics, 2018 - cell.com
Since their discovery Hox genes have been at the core of the established models explaining
the development and evolution of the vertebrate body plan as well as its paired …

The chromatin insulator CTCF and the emergence of metazoan diversity

P Heger, B Marin, M Bartkuhn… - Proceedings of the …, 2012 - National Acad Sciences
The great majority of metazoans belong to bilaterian phyla. They diversified during a short
interval in Earth's history known as the Cambrian explosion,∼ 540 million years ago …

The rise of genomics in snake venom research: recent advances and future perspectives

W Rao, K Kalogeropoulos, ME Allentoft… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …