Management of endothelial dysfunction in systemic sclerosis: current and developing strategies

DC Zanin-Silva, M Santana-Gonçalves… - Frontiers in …, 2021 - frontiersin.org
Systemic Sclerosis (SSc) is an autoimmune disease marked by dysregulation of the immune
system, tissue fibrosis and dysfunction of the vasculature. Vascular damage, remodeling and …

Involvement of phosphatidylserine receptors in the skeletal muscle regeneration: therapeutic implications

Z Szondy, N Al‐Zaeed, N Tarban, É Fige… - Journal of Cachexia …, 2022 - Wiley Online Library
Sarcopenia is a progressive loss of muscle mass and strength with a risk of adverse
outcomes such as disability, poor quality of life, and death. Increasing evidence indicates …

Recognising the spectrum of scleromyositis: HEp-2 ANA patterns allow identification of a novel clinical subset with anti-SMN autoantibodies

O Landon-Cardinal, A Baril-Dionne, S Hoa, A Meyer… - RMD open, 2020 - rmdopen.bmj.com
Objective To describe systemic sclerosis (SSc) with myopathy in patients without classic SSc-
specific and SSc-overlap autoantibodies (aAbs), referred to as seronegative scleromyositis …

Effect of THBS1 on the biological function of hypertrophic scar fibroblasts

D Jiang, B Guo, F Lin, Q Hui… - BioMed research …, 2020 - Wiley Online Library
Hypertrophic scarring is a skin collagen disease that can occur following skin damage and is
unlikely to heal or subside naturally. Since surgical treatment often worsens scarring, it is …

The increasing role of muscle MRI to monitor changes over time in untreated and treated muscle diseases

C Nuñez-Peralta, J Alonso-Pérez… - Current Opinion in …, 2020 - journals.lww.com
The latest results obtained from the study of long cohorts of patients with various
neuromuscular diseases open the door to the use of this technology in clinical trials, which …

Systemic sclerosis-associated myopathy: How to treat

A Selva-O'Callaghan, A Guillen-Del-Castillo… - … treatment options in …, 2023 - Springer
Abstract Purpose of Review Systemic sclerosis (SSc) and myositis are two different entities
that may coexist as an overlap syndrome. Immunological biomarkers such as anti-PM/Scl or …

Inflammatory myopathies overlapping with systemic sclerosis: a systematic review

JG Júnior, N Mugii, PT Inaoka, PD Sampaio-Barros… - Clinical …, 2022 - Springer
We performed a systematic review of the clinical manifestations and complementary exams
of patients with myopathies and systemic sclerosis overlap syndrome (MyoSScOS) …

[HTML][HTML] ADAMTS proteases and the tumor immune microenvironment: Lessons from substrates and pathologies

S Redondo-García, C Peris-Torres… - Matrix biology plus, 2021 - Elsevier
The relationship of ADAMTS (a disintegrin and metalloproteinase with thrombospondin
motifs) proteases with inflammatory processes was anticipated since their discovery …

[HTML][HTML] Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling

M Flores-Opazo, D Kopinke, F Helmbacher… - Molecular Aspects of …, 2024 - Elsevier
Excessive accumulation of intermuscular adipose tissue (IMAT) is a common pathological
feature in various metabolic and health conditions and can cause muscle atrophy, reduced …

[HTML][HTML] Systemic Sclerosis and Atherosclerosis: Potential Cellular Biomarkers and Mechanisms

EV Gerasimova, RU Shayakhmetova… - Frontiers in Bioscience …, 2023 - imrpress.com
Systemic sclerosis (SSc) is a rare systemic autoimmune disease of unknown etiology, which
is characterized by endothelial dysfunction, pathologic vasculopathy, and increased tissue …