Background Point of-care (POC) HIV-1 RNA tests which are accurate and easy to use with
limited infrastructure are needed in resource-limited settings (RLS). We systematically …

Although 23 antiretroviral drugs are approved for use in adults, only six are approved by
regulatory authorities for use in term neonates born to women with HIV, with even fewer …

Background As the number of HIV-infected women initiating lifelong antiretroviral therapy
(ART) during pregnancy increases globally, concerns have emerged regarding low levels of …

Background HIV Viral Load and Early Infant Diagnosis technologies in many high burden
settings are restricted to centralized laboratory testing, leading to long result turnaround …

Worldwide, nearly two million children are infected with human immunodeficiency virus
(HIV), with breastfeeding accounting for the majority of contemporary HIV transmissions …

Introduction The scale‐up of effective HIV viral load (VL) testing is an urgent public health
priority. Implementation of testing is supported by the availability of accurate, nucleic acid …

Background: Despite progress, 2016 still saw 160,000 new infections and 120,000 AIDS-
related deaths among children. Evidence gaps on how to best diagnose, treat, and deliver …

The global HIV response has been remarkably successful. More than 19 million persons
living with HIV (PLHIV) have accessed life-saving antiretroviral therapy (ART)[1] and the …

Objectives Early infant diagnosis (EID) of HIV infection increases antiretroviral therapy
initiation, which reduces pediatric HIV-related morbidity and mortality. This review aims to …

Background Early identification of HIV-infected infants for treatment is critical for survival.
Efficient uptake of early infant diagnosis (EID) requires timely presentation of HIV-exposed …