Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …

The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Bitter taste receptors (taste 2 receptors, TAS2Rs) serve as warning sensors in the lingual
system against the ingestion of potentially poisonous food. Here, we investigated the …

The incidence of obesity has dramatically increased in recent years, and poses a public
health challenge for which an effective and scalable intervention strategy is yet to be found …

Ultra-processed foods and drinks (UPF) are formulation of ingredients, mostly of exclusive
industrial use, that result from a series of industrial processes. They usually have a low …

Obesity is a multifactorial disease with several potential causes that remain incompletely
understood. Recent changes in the environment, which has become increasingly …

Background Our sense of taste is critical in defining our food choices and habits. Located
primarily in our tongue, taste buds are small assemblies of constantly renewing sensory …

Premature obesity-related mortality is caused by cardiovascular and pulmonary diseases,
type 2 diabetes mellitus, physical disabilities, osteoarthritis, and certain types of cancer …

Although genetics shapes our sense of taste to prefer some foods over others, taste
sensation is plastic and changes with age, disease state, and nutrition. We have known for …

Key Points Physiological Integration of Taste and Metabolism The tongue taste map that we
all learned in school is wrong; taste receptor cells responsive to each of the tastes are …