Chemical tagging in mass spectrometry for systems biology

T Huang, MR Armbruster, JB Coulton… - Analytical …, 2018 - ACS Publications
Mass spectrometry (MS) offers unparalleled qualitative and quantitative chemical
information. While increasingly considered a universal detector, the limitations of MS to …

Use of plasma-free amino acids as biomarkers for detecting and predicting disease risk

K Nagao, T Kimura - Nutrition reviews, 2020 - academic.oup.com
This paper reviews developments regarding the use of plasma-free amino acid (PFAA)
profiles as biomarkers for detecting and predicting disease risk. This work was initiated and …

Intradermal glycine detection with a wearable microneedle biosensor: the first in vivo assay

Q Wang, A Molinero-Fernandez, A Casanova… - Analytical …, 2022 - ACS Publications
Glycine (GLY) is gaining importance in medical diagnoses due to its relationship with
multiple physiological functions. Today, GLY is exclusively analyzed using instrumentation …

[HTML][HTML] Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk-and peanut paste–based formulation for treating severe acute …

P Bahwere, B Balaluka, JCK Wells… - The American journal of …, 2016 - Elsevier
abstract Background: The cost of current standard ready-to-use therapeutic food (RUTF) is
among the major obstacles to scaling up community-based management of acute …

Decreased circulating branched-chain amino acids are associated with development of Alzheimer's disease in elderly individuals with mild cognitive impairment

T Ikeuchi, M Kanda, H Kitamura, F Morikawa… - Frontiers in …, 2022 - frontiersin.org
Background Nutritional epidemiology has shown that inadequate dietary protein intake is
associated with poor brain function in the elderly population. The plasma free amino acid …

Enhancing Bioactivity and Conjugation in Green Coffee Bean (Coffea arabica) Extract through Cold Plasma Treatment: Insights into Antioxidant Activity and Phenolic …

K Kungsuwan, C Sawangrat, S Ounjaijean, S Chaipoot… - Molecules, 2023 - mdpi.com
Cold plasma technology is gaining attention as a promising approach to enhancing the
bioactivity of plant extracts. However, its impact on green coffee bean extracts (GCBEs) still …

Polypyrrole/carbon dot nanocomposite as an electrochemical biosensor for liquid biopsy analysis of tryptophan in the human serum of normal and breast cancer …

FAM Abdel-Aal, RM Kamel, AA Abdeltawab… - Analytical and …, 2023 - Springer
Liquid biopsy analysis represents a suitable alternative analysis procedure in several cases
where no tumor tissue is available or in poor patient conditions. Amino acids can play a …

[HTML][HTML] Determination of underivatized amino acids in human plasma using ion pair liquid chromatography/tandem mass spectrometry

C Turner, H Refsum, NE Bastani - Journal of Chromatography B, 2023 - Elsevier
Accurate quantification of amino acids (AA) is essential for several applications, including
clinical research, food analysis, and pharmaceutical studies. In this study, we developed an …

A reliable LC-MS/MS method for the quantification of natural amino acids in mouse plasma: method validation and application to a study on amino acid dynamics …

Z Liu, MJ Tu, C Zhang, JL Jilek, QY Zhang… - … of Chromatography B, 2019 - Elsevier
A simple and fast LC-MS/MS method was developed and validated for simultaneous
quantification of 20 proteinogenic l-amino acids (AAs) in a small volume (5 μL) of mouse …

Plasma amino acid profile associated with fatty liver disease and co-occurrence of metabolic risk factors

M Yamakado, T Tanaka, K Nagao, A Imaizumi… - Scientific Reports, 2017 - nature.com
Fatty liver disease (FLD) increases the risk of diabetes, cardiovascular disease, and
steatohepatitis, which leads to fibrosis, cirrhosis, and hepatocellular carcinoma. Thus, the …