Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

Aims Recently, cancer-derived exosomes were shown to have pro-metastasis function in
cancer, but the mechanism remains unclear. Angiogenesis is essential for tumor …

Renal cell carcinoma (RCC) is characterized by an infrequent number of somatic mutations.
By contrast, epigenetic aberrations are commonly found in RCC, indicating that epigenetic …

Abstract Background Secreted microRNAs (miRNAs) can serve as promising diagnostic
markers for colorectal cancer (CRC). Herein, we evaluated the potential clinical significance …

A novel coronavirus appeared in Wuhan, China has led to major outbreaks. Recently, rapid
classification of virus species, analysis of genome and screening for effective drugs are the …

Since their discovery and the advent of RNA interference, microRNAs have drawn enormous
attention because of their ubiquitous involvement in cellular pathways from life to death, from …

Although decision making strategy based on clinico-histopathological criteria is well
established, renal cell carcinoma (RCC) represents a spectrum of biological ecosystems …

Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it
has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has …

Downregulation of miR-221-3p expression in prostate cancer (PCa) predicted overall and
cancer-specific survival of high-risk PCa patients. Apart from PCa, miR-221-3p expression …