[HTML][HTML] Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM)

T Simmen, EM Lynes, K Gesson, G Thomas - Biochimica et Biophysica Acta …, 2010 - Elsevier
The production of secretory proteins at the ER (endoplasmic reticulum) depends on a ready
supply of energy and metabolites as well as the close monitoring of the chemical conditions …

New insights into the role of mitochondria-associated endoplasmic reticulum membrane

M Fujimoto, T Hayashi - International review of cell and molecular biology, 2011 - Elsevier
The mitochondria-associated endoplasmic reticulum membrane (MAM) is a specialized
subdomain of the endoplasmic reticulum (ER) membrane that regulates ER–mitochondria …

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs

V Manganelli, P Matarrese, M Antonioli… - Autophagy, 2021 - Taylor & Francis
Mitochondria-associated membranes (MAMs) are essential communication subdomains of
the endoplasmic reticulum (ER) that interact with mitochondria. We previously demonstrated …

Protein–protein and protein–membrane associations in the lignin pathway

JE Bassard, L Richert, J Geerinck, H Renault… - The Plant …, 2012 - academic.oup.com
Supramolecular organization of enzymes is proposed to orchestrate metabolic complexity
and help channel intermediates in different pathways. Phenylpropanoid metabolism has to …

Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection

A Zhang, CD Williamson, DS Wong… - Molecular & Cellular …, 2011 - ASBMB
Endoplasmic reticulum-mitochondrial contacts, known as mitochondria-associated
membranes, regulate important cellular functions including calcium signaling, bioenergetics …

The Arabidopsis Prohibitin Gene PHB3 Functions in Nitric Oxide–Mediated Responses and in Hydrogen Peroxide–Induced Nitric Oxide Accumulation

Y Wang, A Ries, K Wu, A Yang, NM Crawford - The Plant Cell, 2010 - academic.oup.com
To discover genes involved in nitric oxide (NO) metabolism, a genetic screen was employed
to identify mutants defective in NO accumulation after treatment with the physiological …

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1, 4, 5-trisphosphate …

MMP Pearce, DB Wormer, S Wilkens… - Journal of Biological …, 2009 - ASBMB
How endoplasmic reticulum (ER) proteins that are substrates for the ER-associated
degradation (ERAD) pathway are recognized for polyubiquitination and proteasomal …

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

MD Huber, PW Vesely, K Datta, L Gerace - Journal of Cell Biology, 2013 - rupress.org
Cellular cholesterol levels are controlled by endoplasmic reticulum (ER) sterol sensing
proteins, which include Scap and Insig-1. With cholesterol sufficiency, Insig inhibits the …

Role of ERLINs in the control of cell fate through lipid rafts

V Manganelli, A Longo, V Mattei, S Recalchi, G Riitano… - Cells, 2021 - mdpi.com
ER lipid raft-associated protein 1 (ERLIN1) and 2 (ERLIN2) are 40 kDa transmembrane
glycoproteins belonging to the family of prohibitins, containing a PHB domain. They are …

Cholesterol at the endoplasmic reticulum: roles of the sigma-1 receptor chaperone and implications thereof in human diseases

T Hayashi, TP Su - … Binding and Cholesterol Transport Proteins: Structure …, 2010 - Springer
Despite substantial data elucidating the roles of cholesterol in lipid rafts at the plasma
membrane, the roles of cholesterol and related lipids in lipid raft microdomains at the level of …