Environmental influences on the pace of brain development

UA Tooley, DS Bassett, AP Mackey - Nature Reviews Neuroscience, 2021 - nature.com
Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

Stress and health: A review of psychobiological processes

DB O'Connor, JF Thayer… - Annual review of …, 2021 - annualreviews.org
The cumulative science linking stress to negative health outcomes is vast. Stress can affect
health directly, through autonomic and neuroendocrine responses, but also indirectly …

Allostatic load and its impact on health: a systematic review

J Guidi, M Lucente, N Sonino, GA Fava - Psychotherapy and …, 2020 - karger.com
Introduction: Allostatic load refers to the cumulative burden of chronic stress and life events.
It involves the interaction of different physiological systems at varying degrees of activity …

Early life stress and development: potential mechanisms for adverse outcomes

KE Smith, SD Pollak - Journal of neurodevelopmental disorders, 2020 - Springer
Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Objective and subjective experiences of child maltreatment and their relationships with psychopathology

A Danese, CS Widom - Nature human behaviour, 2020 - nature.com
Does psychopathology develop as a function of the objective or subjective experience of
childhood maltreatment? To address this question, we studied a unique cohort of 1,196 …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Life course health consequences and associated annual costs of adverse childhood experiences across Europe and North America: a systematic review and meta …

MA Bellis, K Hughes, K Ford, GR Rodriguez… - The Lancet Public …, 2019 - thelancet.com
Background An increasing number of studies are identifying associations between adverse
childhood experiences (ACEs) and ill health throughout the life course. We aimed to …

Making the “C-ACE” for a culturally-informed adverse childhood experiences framework to understand the pervasive mental health impact of racism on Black youth

DL Bernard, CD Calhoun, DE Banks… - Journal of Child & …, 2021 - Springer
The high prevalence and psychological impact of childhood exposure to potentially
traumatic events (PTE) is a major public health concern in the United States. Considerable …

The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis

K Hughes, MA Bellis, KA Hardcastle, D Sethi… - The Lancet public …, 2017 - thelancet.com
Background A growing body of research identifies the harmful effects that adverse childhood
experiences (ACEs; occurring during childhood or adolescence; eg, child maltreatment or …

Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

DW Belsky, A Caspi, L Arseneault, A Baccarelli… - Elife, 2020 - elifesciences.org
Biological aging is the gradual, progressive decline in system integrity that occurs with
advancing chronological age, causing morbidity and disability. Measurements of the pace of …