During breed development, domestic dogs have undergone genetic bottlenecks and
sustained selective pressures, as a result distinctive genomic diversity occurs to varying …

High-altitude pulmonary edema (HAPE) is noncardiogenic lung edema characterized by
elevated pulmonary artery pressures, dyspnea, cough, and reduced exercise capacity. In …

The dramatic changes in physiology at high altitude (HA) as a result of the characteristic
hypobaric hypoxia condition can modify innate and adaptive defense mechanisms of the …

High-altitude pulmonary edema (HAPE) is a common acute altitude sickness. This study was
designed to investigate the effect of MIR17HG polymorphisms on HAPE risk in the Chinese …

Background: Environmental and genetic factors are jointly involved in the development of
chronic obstructive pulmonary disease (COPD). The EGLN1 gene is a major factor in …

Abstract Background High-altitude (HA, 2500 m) hypoxic exposure evokes a multitude of
physiological processes. The hypoxia-sensing genes though influence transcriptional output …

High-altitude pulmonary edema (HAPE) and COVID-19 pneumonia are different diseases,
but HAPE-susceptible individuals (whose susceptibility often has a genetic basis) can also …

Autophagy has been implicated in the pathogenesis of various lung diseases. This study
aimed to investigate the role of autophagy in lung injury induced by high‐altitude hypoxia …