Recent advances in transition metal-catalyzed heteroannulative difunctionalization of alkenes via C–H activation for the synthesis of heterocycles

J Liu, X Xiao, Y Lai, Z Zhang - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Heterocyclic compounds are the fundamental structural motifs distributed in natural
products, pharmaceuticals and biologically active compounds. Thus, there is increasing …

Recent advances in cobalt-catalysed C–H functionalizations

A Baccalini, S Vergura, P Dolui, G Zanoni… - Organic & Biomolecular …, 2019 - pubs.rsc.org
Ready availability, low cost and low toxicity of cobalt salts have redirected the attention of
researchers away from noble metals, such as Pd, Rh, and Ir, towards Co in the field of C–H …

Cobalt-catalyzed enantioselective C–H annulation with alkenes

D Yang, X Zhang, X Wang, XJ Si, J Wang, D Wei… - ACS …, 2023 - ACS Publications
Herein, we disclose an efficient cobalt-catalyzed enantioselective C–H activation and
annulation of benzamides with alkenes. This transformation is facilitated via the …

Cobalt‐Catalyzed Oxidative C− H Activation: Strategies and Concepts

R Mei, U Dhawa, RC Samanta, W Ma… - …, 2020 - Wiley Online Library
Inexpensive cobalt‐catalyzed oxidative C− H functionalization has emerged as a powerful
tool for the construction of C− C and C− Het bonds, which offers unique potential for …

Traceless Bidentate Directing Group Assisted Cobalt-Catalyzed sp2-C–H Activation and [4 + 2]-Annulation Reaction with 1,3-Diynes

A Dey, CMR Volla - Organic Letters, 2020 - ACS Publications
An efficient cobalt-catalyzed [4+ 2] annulation of hydrazones and 1, 3-diynes has been
developed for the synthesis of 3-alkynylated isoquinolines engaging 2-aminopyridine as a …

Recent advances in directed sp 2 C–H functionalization towards the synthesis of N-heterocycles and O-heterocycles

B Desai, M Patel, BZ Dholakiya, S Rana… - Chemical …, 2021 - pubs.rsc.org
Heterocyclic compounds are widely present in the core structures of several natural
products, pharmaceuticals and agrochemicals, and thus great efforts have been devoted to …

Rh (III)-Catalyzed Dienylation and Cyclopropylation of 1, 2, 3-Benzotriazinones with Alkylidenecyclopropanes

YZ Liu, YF Zeng, J Wei, L Xiao, B Shu, JL Song… - Organic …, 2023 - ACS Publications
Rh (III)-catalyzed dienylation and cyclopropylation of 1, 2, 3-benzotriazinones with
alkylidenecyclopropanes (ACPs) has been achieved. Different from the previous reports of …

Cobalt-catalyzed radical-mediated carbon–carbon scission via a radical-type migratory insertion

JB Liu, XJ Liu, JCA Oliveira, DZ Chen… - Chemical Science, 2023 - pubs.rsc.org
Migratory insertions of alkenes into metal–carbon (M–C) bonds are elementary steps in
diverse catalytic processes. In the present work, a radical-type migratory insertion that …

Iron-catalyzed ortho C–H homoallylation of aromatic ketones with methylenecyclopropanes

N Kimura, S Katta, Y Kitazawa, T Kochi… - Journal of the …, 2021 - ACS Publications
We report here a C–H homoallylation reaction of aromatic ketones with
methylenecyclopropanes (MCPs) only using a catalytic amount of Fe (PMe3) 4. A variety of …

Visible-light-promoted divergent functionalizations of methylenecyclopropanes

B Zhu, Z Wang, H Xi, Z Feng, B Wang, W Jiao… - Organic Chemistry …, 2021 - pubs.rsc.org
Simple and convenient visible-light-promoted radical monofunctionalization and
difunctionalization of methylenecyclopropanes via ring-opening and cyclization processes …