Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids

O Tartagni, A Borók, E Mensà, A Bonyár… - Cellular and Molecular …, 2023 - Springer
Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with
respect to more traditional 2D culturing. Microwell culturing is a simple and accessible …

[HTML][HTML] Super liquid-repellent surfaces and 3D spheroids growth

M Ferrari, F Cirisano, MC Morán - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
Substrates composition and surface features of materials rule adhesion control of cells to
surfaces. As a result, most of the aspects of cell functions, such as spreading, migration …

Combinatorial drug screening based on massive 3d tumor cultures using micropatterned array chips

W Fu, M Sun, J Zhang, T Xuanyuan, X Liu… - Analytical …, 2023 - ACS Publications
The establishment and application of a generalizable three-dimensional (3D) tumor device
for high-throughput screening plays an important role in drug discovery and cancer …

Mammalian cell spheroids on mixed organic–inorganic superhydrophobic coating

M Ferrari, F Cirisano, MC Morán - Molecules, 2022 - mdpi.com
Three-dimensional cell culture has become a reliable method for reproducing in vitro
cellular growth in more realistic physiological conditions. The surface hydrophobicity …

Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method

H Guo, H Yu, H Zu, J Cui, H Ding, Y Xia, D Chen… - Toxicology Letters, 2023 - Elsevier
Cell spheroid culture can recapitulate the tissue microstructure and cellular responses in
vivo. While there is a strong need to understand the modes of toxic action using the spheroid …