The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with
high affinity and specificity. The process of selecting an aptamer is called Systematic …

Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Background Nucleic acid aptamers, defined as small functional nucleic acids that can
selectively bind to a specific target, have become one of the main bio-recognition elements …

Systematic evolution of ligand by exponential enrichment (SELEX) is an efficient method
used to isolate high-affinity single stranded oligonucleotides from a large random sequence …

The early detection of cancer favors a greater chance of curative treatment and long-term
survival. Exciting new technologies have been developed that can help to catch the disease …

We developed an efficient and fast method based on a protein microarray integrated with a
microfluidic chip for the process of SELEX (systematic evolution of ligands by exponential …

We validated a single-stranded, DNA aptamer-based, diagnostic method capable of
detecting Lipocalin-2 (LCN2), a biomarker from clinically relevant hepatocellular carcinoma …

Aptamers are sequences of single-strand oligonucleotides (DNA or RNA) with potential
binding capability to specific target molecules, which are increasingly used as agents for …

Nucleic acid aptamers have tremendous potential as molecular recognition elements in
biomedical targeting, analytical arrays, and self-signaling sensors. However, practical …