Cerebellar ataxias with autosomal dominant transmission are rare, but identification of the
associated genes has provided insight into the mechanisms that could underlie other forms …

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia that
occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive …

The inherited cerebellar ataxias are a diverse group of clinically and genetically
heterogeneous neurodegenerative disorders. Inheritance patterns of these disorders can be …

Over the last decade, studies have implicated the cerebellum not only in motor functioning,
but also in cognition and social cognition. Although some aspects of cognition have been …

Abstract Spinocerebellar ataxia type 12 (SCA12) is a rare neurodegenerative disorder
caused by CAG repeat expansion in the PPP2R2B gene. Previously, the causal length of …

Spinocerebellar ataxias (SCAs) comprise a heterogeneous group of autosomal dominant
disorders. The relative frequency of the different SCA subtypes varies broadly among …

Cerebellar ataxias (CAs) represent a group of autosomal dominant and recessive
neurodegenerative disorders affecting cerebellum with or without spinal cord. Overall, CAs …

Circular RNAs (ciRNAs) are emerging as new players in the regulation of gene expression.
However, how ciRNAs are involved in neuropathic pain is poorly understood. Here, we …

Dominantly inherited ataxias (spinocerebellar ataxias, SCAs) are a genetically
heterogeneous group of neurologic diseases characterized by progressive cerebellar and …

An intronic bi-allelic pentanucleotide repeat expansion mutation,(AAGGG) 400–2000, at
AAAAG repeat locus in RFC1 gene, is known as underlying genetic cause in cases with …