IL-7 receptor signaling drives human B-cell progenitor differentiation and expansion

FMP Kaiser, I Janowska, R Menafra, M de Gier… - Blood, 2023 - ashpublications.org
Although absence of interleukin-7 (IL-7) signaling completely abrogates T and B
lymphopoiesis in mice, patients with severe combined immunodeficiency caused by …

Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling

X Feng, R Sun, M Lee, X Chen, S Guo, H Geng… - Elife, 2023 - elifesciences.org
Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify
the bone marrow microenvironment and disrupt non-malignant hematopoiesis. However, the …

[HTML][HTML] Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing …

H Xiao, Y Wang, Z Wang, B Wang, L Hu, J Hou… - Biomedicine & …, 2023 - Elsevier
B-lymphocytopenia among myelosuppression is the most intractable side effect of
chemotherapy. Here, we investigated ways to alleviate 5-fluorouracil-caused stress …

间充质干细胞治疗自身免疫性肝病的临床研究进展.

史婉婉, 钱建丹, 王贵强 - Journal of Clinical Hepatology …, 2023 - search.ebscohost.com
自身免疫性肝病因治疗选择和方式比较局限, 因此迫切需要寻求新的治疗方法.
间充质干细胞(MSC) 作为干细胞治疗最常见的细胞来源, 在调节先天和适应性免疫反应中发挥着 …

Clinical research advances in mesenchymal stem cells for the treatment of autoimmune liver diseases

SHI Wanwan, Q Jiandan - 临床肝胆病杂志, 2023 - lcgdbzz.org
Due to limited options and modalities for the etiological treatment of autoimmune liver
diseases, it is urgent to seek new therapeutic methods for liver autoimmune diseases. As the …