Atherosclerosis is a leading cause of cardiovascular disease worldwide, and
hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the …

Alzheimer's disease (AD) is the most common type of dementia, mainly encompassing
cognitive decline in subjects aged≥ 65 years. Further, AD is characterized by selective …

High-fat diet and certain dietary patterns are associated with higher incidence of sporadic
Alzheimer's disease (AD) and cognitive decline. However, no specific therapy has been …

In the present review we provide a summary of ATP-binding cassette (ABC) transporters in
the central nervous system (CNS). Our review is focused on transporters of the ABC A, B, C …

ATP-binding cassette transporter A1—ABCA1, is the most extensively studied transporter in
human pathology. ABCA1 became a primary subject of research in many academic and …

Abstract The two Liver X Receptors, LXRα and LXRβ, are nuclear receptors belonging to the
superfamily of ligand-activated transcription factors. They share more than 78% homology in …

Early growth response gene 1 (Egr1) is a member of the immediate early gene (IEG) family
of transcription factors and plays a role in memory formation. To identify EGR1 target genes …

Liver X receptors (LXRs) are nuclear receptors involved in the regulation of lipid metabolism
and inflammatory responses in the central nervous system. Defects in cholesterol …

Four new pterosin sesquiterpenoids (1–4), a new ent-kaurane diterpenoid (17), and 18
known compounds were isolated from the aerial parts of Pteris cretica L. The structures of …

Omeprazole is the most commonly used proton pump inhibitor (PPI), a class of medications
whose therapeutic mechanism of action involves formation of a disulfide linkage to cysteine …