Gradient scaffolds for osteochondral tissue engineering and regeneration

B Zhang, J Huang, RJ Narayan - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The tissue engineering approach for repairing osteochondral (OC) defects involves the
fabrication of a biological tissue scaffold that mimics the physiological properties of natural …

Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations

RA Somoza, JF Welter, D Correa… - Tissue Engineering Part …, 2014 - liebertpub.com
Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

Interwoven aligned conductive nanofiber yarn/hydrogel composite scaffolds for engineered 3D cardiac anisotropy

Y Wu, L Wang, B Guo, PX Ma - Acs Nano, 2017 - ACS Publications
Mimicking the anisotropic cardiac structure and guiding 3D cellular orientation play a critical
role in designing scaffolds for cardiac tissue regeneration. Significant advances have been …

Fiber-based tissue engineering: Progress, challenges, and opportunities

A Tamayol, M Akbari, N Annabi, A Paul… - Biotechnology …, 2013 - Elsevier
Tissue engineering aims to improve the function of diseased or damaged organs by creating
biological substitutes. To fabricate a functional tissue, the engineered construct should …

Biofabrication of osteochondral tissue equivalents by printing topologically defined, cell-laden hydrogel scaffolds

NE Fedorovich, W Schuurman… - … Engineering Part C …, 2012 - liebertpub.com
Osteochondral defects are prone to induce osteoarthritic degenerative changes. Many tissue-
engineering approaches that aim to generate osteochondral implants suffer from poor tissue …

The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review

A Goldberg, K Mitchell, J Soans, L Kim… - Journal of orthopaedic …, 2017 - Springer
Background The management of articular cartilage defects presents many clinical
challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation …

Osteochondral tissue engineering: scaffolds, stem cells and applications

P Nooeaid, V Salih, JP Beier… - Journal of cellular and …, 2012 - Wiley Online Library
Osteochondral tissue engineering has shown an increasing development to provide suitable
strategies for the regeneration of damaged cartilage and underlying subchondral bone …

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

TJ Levingstone, A Matsiko, GR Dickson, FJ O'Brien… - Acta biomaterialia, 2014 - Elsevier
Cartilage and osteochondral defects pose a significant challenge in orthopedics. Tissue
engineering has shown promise as a potential method for the treatment of such defects; …

Textile technologies and tissue engineering: a path toward organ weaving

M Akbari, A Tamayol, S Bagherifard… - Advanced …, 2016 - Wiley Online Library
Textile technologies have recently attracted great attention as potential biofabrication tools
for engineering tissue constructs. Using current textile technologies, fibrous structures can …

Bone defect reconstruction via endochondral ossification: A developmental engineering strategy

R Fu, C Liu, Y Yan, Q Li… - Journal of tissue …, 2021 - journals.sagepub.com
Traditional bone tissue engineering (BTE) strategies induce direct bone-like matrix formation
by mimicking the embryological process of intramembranous ossification. However, the …