[HTML][HTML] Bone marrow adiposity and the hematopoietic niche: A historical perspective of reciprocity, heterogeneity, and lineage commitment

J Tratwal, S Rojas-Sutterlin, C Bataclan, S Blum… - Best Practice & …, 2021 - Elsevier
Purpose Here we review the current knowledge on bone marrow adipocytes (BMAds) as
active contributors to the regulation of the hematopoietic niche, and as potentially pivotal …

Adipocyte-and monocyte-mediated vicious circle of inflammation and obesity (review of cellular and molecular mechanisms)

N Todosenko, O Khaziakhmatova… - International Journal of …, 2023 - mdpi.com
Monocytes play a key role in the development of metabolic syndrome, and especially
obesity. Given the complex features of their development from progenitor cells, whose …

Bone marrow adiposity modulation after long duration spaceflight in astronauts

T Liu, G Melkus, T Ramsay, A Sheikh… - Nature …, 2023 - nature.com
Abstract Space travel requires metabolic adaptations from multiple systems. While vital to
bone and blood production, human bone marrow adipose (BMA) tissue modulation in space …

Gender-and age-associated differences in bone marrow adipose tissue and bone marrow fat unsaturation throughout the skeleton, quantified using chemical shift …

KM Beekman, M Regenboog, AJ Nederveen… - Frontiers in …, 2022 - frontiersin.org
Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with
osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to …

MarrowQuant Across Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

J Tratwal, D Bekri, C Boussema, R Sarkis… - Frontiers in …, 2020 - frontiersin.org
The bone marrow (BM) exists heterogeneously as hematopoietic/red or adipocytic/yellow
marrow depending on skeletal location, age, and physiological condition. Mouse models …

The impact of interventional weight loss on bone marrow adipose tissue in people living with obesity and its connection to bone metabolism

M Tencerova, G Duque, KM Beekman, A Corsi… - Nutrients, 2023 - mdpi.com
This review focuses on providing physicians with insights into the complex relationship
between bone marrow adipose tissue (BMAT) and bone health, in the context of weight loss …

Perilipin-1 immunostaining improves semi-automated digital quantitation of bone marrow adipocytes in histological bone sections

N Widjaja, N Jalava, Y Chen, KK Ivaska - Adipocyte, 2023 - Taylor & Francis
Bone marrow adipocytes (BMAds) are not just passive fillers inside the bone marrow
compartment but respond to various metabolic changes. Assessment of those responses …

Bone marrow adipocytes: A link between obesity and bone cancer

MR Reagan, H Fairfield, CJ Rosen - Cancers, 2021 - mdpi.com
Simple Summary This review discusses the important newly-established roles for bone
marrow adipose tissue in cancer progression and highlights the research demonstrating …

Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes

J Tratwal, G Falgayrac, A During… - Frontiers in …, 2022 - frontiersin.org
Bone marrow adipocytes (BMAds) constitute the most abundant stromal component of adult
human bone marrow. Two subtypes of BMAds have been described, the more labile …

Disturbed bone marrow adiposity in patients with Cushing's syndrome and glucocorticoid-and postmenopausal-induced osteoporosis

NN Sørensen, CM Andreasen, PR Jensen… - Frontiers in …, 2023 - frontiersin.org
Background Skeletal stem/progenitor cells (SSPCs) in the bone marrow can differentiate into
osteoblasts or adipocytes in response to microenvironmental signalling input, including …