The long-established observation that some rheumatologic disorders (RDs) are associated
with–or precede–the clinical manifestations of a variety of solid and hematological tumors …

The association between malignancy and autoimmune myositis has been largely described
and confirmed by numerous epidemiological studies. The temporal relationship between the …

Abstract Interleukin-1β (IL-1β) is a pleiotropic cytokine that exerts multiple roles in both
physiological and pathological conditions. It is produced by different cell subsets, and drives …

Idiopathic inflammatory myopathies are a group of rare connective tissue diseases with a
well-documented association with malignancy. The mechanisms underlying the increased …

Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections
within the human genome. These molecular fossils draw parallels with present-day …

Paraneoplastic symptoms, caused by a malignancy, but not directly related to invasion by
the tumor or its metastases, are the result of a wide variety of tumor-derived biologic …

Background Malignant neoplasms are a well-recognized global public health concern, with
significant impacts on human health and quality of life. The interplay between tumors and …

Autoimmune diseases (ADs) are associated with an increased risk not only of
lymphoproliferative disorders but also of myeloid malignancies. The excess risk of …

The link between malignancies and rheumatic disorders may impact on clinical practice.
First, paraneoplastic rheumatic syndromes can provide the clinician with hints for earlier …

Background Cardiac tumours are rare, and clinical manifestations depend on the anatomical
location. Symptoms can be the result of cardiac outflow anomalies, constitutional features …