Endoscopic lung volume reduction (ELVR) is being adopted as a treatment option for
carefully selected patients suffering from severe emphysema. ELVR with the one-way …

For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay
for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway …

Background Bronchoscopic lung-volume reduction with the use of one-way endobronchial
valves is a potential treatment for patients with severe emphysema. To date, the benefits …

Rationale: Endobronchial valves (EBVs) have been successfully used in patients with
severe heterogeneous emphysema to improve lung physiology. Limited available data …

Rationale: Single-center randomized controlled trials of the Zephyr endobronchial valve
(EBV) treatment have demonstrated benefit in severe heterogeneous emphysema. This is …

Rationale: This is the first multicenter randomized controlled trial to evaluate the
effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little to no …

Background Lung volume reduction surgery improves survival in selected patients with
emphysema, and has generated interest in bronchoscopic approaches that might achieve …

Rationale: Less invasive, nonsurgical approaches are needed to treat severe emphysema.
Objectives: To evaluate the effectiveness and safety of the Spiration Valve System (SVS) …

Endoscopic lung volume reduction (ELVR) therapies are gaining prominence as a treatment
option with guideline recommendations by COPD GOLD and NICE and the recent FDA …

Background Lung volume reduction surgery (LVRS) and bronchoscopic lung volume
reduction (BLVR) with endobronchial valves can improve outcomes in appropriately …