Branched chain amino acids: beyond nutrition metabolism

C Nie, T He, W Zhang, G Zhang, X Ma - International journal of molecular …, 2018 - mdpi.com
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …

Coordinated modulation of energy metabolism and inflammation by branched-chain amino acids and fatty acids

Z Ye, S Wang, C Zhang, Y Zhao - Frontiers in endocrinology, 2020 - frontiersin.org
As important metabolic substrates, branched-chain amino acids (BCAAs) and fatty acids
(FAs) participate in many significant physiological processes, such as mitochondrial …

The role of the gut microbiota in health and cardiovascular diseases

L Wang, S Wang, Q Zhang, C He, C Fu, Q Wei - Molecular biomedicine, 2022 - Springer
The gut microbiota is critical to human health, such as digesting nutrients, forming the
intestinal epithelial barrier, regulating immune function, producing vitamins and hormones …

Metformin promotes anxiolytic and antidepressant-like responses in insulin-resistant mice by decreasing circulating branched-chain amino acids

J Zemdegs, H Martin, H Pintana, S Bullich… - Journal of …, 2019 - Soc Neuroscience
Epidemiological studies indicate that insulin resistance (IR), a hallmark of type 2 diabetes, is
associated with an increased risk of major depression. Here, we demonstrated that male …

Protein supplements and their relation with nutrition, microbiota composition and health: is more protein always better for sportspeople?

A Kårlund, C Gómez-Gallego, AM Turpeinen… - Nutrients, 2019 - mdpi.com
Sports nutrition products are developed and targeted mainly for athletes to improve their
nutrient intake, performance, and muscle growth. The fastest growing consumer groups for …

High animal protein diet and gut microbiota in human health

J Cai, Z Chen, W Wu, Q Lin, Y Liang - Critical Reviews in Food …, 2022 - Taylor & Francis
The role of the intestinal flora in health and disease has become a research hotspot.
Compared with carbohydrates and fats, proteins are metabolized primarily by microbial …

[HTML][HTML] Animal and plant protein sources and cardiometabolic health

F Mariotti - Advances in nutrition, 2019 - Elsevier
The sources or types of protein in the diet have long been overlooked regarding their link to
cardiometabolic health. The picture is complicated by the fact that animal and plant proteins …

Atherosclerosis linked to aberrant amino acid metabolism and immunosuppressive amino acid catabolizing enzymes

BL Zaric, JN Radovanovic, Z Gluvic, AJ Stewart… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular disease is the leading global health concern and responsible for more
deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory …

Effects of branched-chain amino acid–rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: A systematic review and meta-analysis

GH Bai, MC Tsai, WH Hou - Archives of Physical Medicine and …, 2021 - Elsevier
Objectives Protein supplements can improve the loss of muscle in older people. However,
existing reviews have pooled supplements from amino acids to food products together to …

Actions of metformin in the brain: a new perspective of metformin treatments in related neurological disorders

N Li, T Zhou, E Fei - International Journal of Molecular Sciences, 2022 - mdpi.com
Metformin is a first-line drug for treating type 2 diabetes mellitus (T2DM) and one of the most
commonly prescribed drugs in the world. Besides its hypoglycemic effects, metformin also …