Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

Natural history and progression of metabolic dysfunction-associated steatotic liver disease

H Hagström, Y Shang, H Hegmar… - … Lancet Gastroenterology & …, 2024 - thelancet.com
The natural history of metabolic dysfunction-associated steatotic liver disease (MASLD),
previously referred to as non-alcoholic fatty liver disease (NAFLD), is complex and long. A …

AASLD Practice Guideline on imaging-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, A Duarte-Rojo, K Patel, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) is associated with approximately two million annual deaths
worldwide and is an enormous health burden.[1, 2] The majority of liver-related outcomes …

[HTML][HTML] High-throughput, machine learning–based quantification of steatosis, inflammation, ballooning, and fibrosis in biopsies from patients with nonalcoholic fatty …

R Forlano, BH Mullish, N Giannakeas… - Clinical …, 2020 - Elsevier
Background & Aims Liver biopsy is the reference standard for staging and grading
nonalcoholic fatty liver disease (NAFLD), but histologic scoring systems are semiquantitative …

Quantitative functional evaluation of liver fibrosis in mice with dynamic contrast-enhanced photoacoustic imaging

J Lv, Y Xu, L Xu, L Nie - Radiology, 2021 - pubs.rsna.org
Background Dynamic contrast-enhanced (DCE) photoacoustic (PA) imaging (PAI) is a novel
noninvasive imaging modality that uses the differences in optical absorption of …

Liver stiffness by transient elastography to detect porto‐sinusoidal vascular liver disease with portal hypertension

L Elkrief, M Lazareth, S Chevret, V Paradis… - …, 2021 - Wiley Online Library
Background and Aims Porto‐sinusoidal vascular liver disease (PSVD) is a rare cause of
portal hypertension. PSVD is still often misdiagnosed as cirrhosis, emphasizing the need to …

Distinct structural and dynamic components of portal hypertension in different animal models and human liver disease etiologies

P Königshofer, BS Hofer, K Brusilovskaya… - Hepatology, 2022 - journals.lww.com
Distinct structural and dynamic components of portal hyperte... : Hepatology Distinct structural
and dynamic components of portal hypertension in different animal models and human liver …

Non-invasive testing and risk-stratification in patients with MASLD

M Zoncapè, A Liguori, EA Tsochatzis - European Journal of Internal …, 2024 - Elsevier
The development and validation of non-invasive fibrosis tests (NITs) has changed clinical
practice in Hepatology over the last 15 years. Metabolic associated steatotic liver disease …

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD

S Gawrieh, D Sethunath, OW Cummings… - Annals of diagnostic …, 2020 - Elsevier
Accurate detection and quantification of hepatic fibrosis remain essential for assessing the
severity of non-alcoholic fatty liver disease (NAFLD) and its response to therapy in clinical …

Staging liver fibrosis by fibroblast activation protein inhibitor PET in a human-sized swine model

A Pirasteh, S Periyasamy, JJ Meudt, Y Liu… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Current methods of staging liver fibrosis have notable limitations. We investigated the utility
of PET in staging liver fibrosis by correlating liver uptake of 68Ga-labeled fibroblast …