CRISPR–Cas is a widespread adaptive immune system in bacteria and archaea that
protects against viral infection by targeting specific invading nucleic acid sequences …

Bacteriophages, viruses that infect and replicate within bacteria, impact bacterial responses
to antibiotics in complex ways. Recent studies using lytic bacteriophages to treat bacterial …

Argonaute proteins use single-stranded RNA or DNA guides to target complementary
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …

Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

The interactions between bacteria and bacteriophage have important roles in the global
ecosystem; in turn changes in environmental parameters affect the interactions between …

It is becoming increasingly clear that antibiotics can both positively and negatively impact
the infectivity of bacteriophages (phage), but the underlying mechanisms often remain …

Plasmids are key disseminators of antimicrobial resistance genes and virulence factors, and
it is therefore critical to predict and reduce plasmid spread within microbial communities. The …

Bacteria have developed different mechanisms to defend against phages, such as
preventing phages from being adsorbed on the surface of host bacteria; through the …

Organisms have evolved a range of constitutive (always active) and inducible (elicited by
parasites) defence mechanisms, but we have limited understanding of what drives the …

Highlights•Bacterial multicellular behavior plays an important role in predatory
interactions.•Small molecules in signaling or chemical defense contribute to phage …