A comprehensive review of vine tea: Origin, research on Materia Medica, phytochemistry and pharmacology

T Zeng, Y Song, S Qi, R Zhang, L Xu, P Xiao - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Vine tea is a popular folk tea that has been consumed in
China for more than 1200 years. It is often used in ethnic medicine by ethnic groups in …

Dihydromyricetin functions as a tumor suppressor in hepatoblastoma by regulating SOD1/ROS pathway

T Guo, X Wang, G Zhang, T Xia, R Zhu, J Tou - Frontiers in Oncology, 2023 - frontiersin.org
Background Hepatoblastoma has an unsatisfactory prognosis, and traditional chemotherapy
has strong side effects. Dihydromyricetin is a flavonoid extracted from a woody vine of the …

LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling

M Gu, Y Chen, Y Feng, Z Tang - Chinese Medicine, 2024 - Springer
Background LanGui tea, a traditional Chinese medicine formulation comprising of
Gynostemma pentaphyllum (Thunb.) Makino, Cinnamomum cassia (L.) J. Presl, and …

Umbelliferone potentiates intestinal protective effect of Lactobacillus Acidophilus against methotrexate-induced intestinal injury: Biochemical and histological study

EHM Hassanein, FEM Ali, MM Sayed, AR Mahmoud… - Tissue and Cell, 2023 - Elsevier
Intestinal injury is a common adverse effect of methotrexate (MTX) therapy, limiting its
clinical use. Despite oxidative stress and inflammation being the most embedded …

Modulation of keap-1/Nrf2/HO-1 and NF-ĸb/caspase-3 signaling pathways by dihydromyricetin ameliorates sodium valproate-induced liver injury

D Emad, AMA Bayoumi, SM Gebril, DME Ali… - Archives of Biochemistry …, 2024 - Elsevier
Nuclear factor erythroid factor 2 (Nrf2) is the key regulatory of the antioxidant response
elements. Also, Nrf2 interacts with nuclear factor kappa B (NF-ĸB) to inhibit subsequent …

Dihydromyricetin Inhibits M1 Macrophage Polarization in Atherosclerosis by Modulating miR‐9‐Mediated SIRT1/NF‐κB Signaling Pathway

Z Yang, T Li, C Wang, M Meng, S Tan… - Mediators of …, 2023 - Wiley Online Library
Dihydromyricetin (DMY), a natural flavonoid compound extracted from the stems and leaves
of Ampelopsis grossedentata, has been found as a potential therapeutic chemical for …

Dihydromyricetin Modulates Nrf2 and NF-κB Crosstalk to Alleviate Methotrexate-Induced Lung Toxicity

AI Matouk, EM Awad, NFG El-Tahawy, AAK El-Sheikh… - Pharmaceuticals, 2023 - mdpi.com
Background: Methotrexate (MTX) is an effective anticancer, anti-inflammatory, and
immunomodulatory agent. However, it induces a serious pneumonitis that leads to …

The beneficial effects of l‐carnitine and infliximab in methotrexate‐induced hepatotoxicity: Emphasis on Notch1/Hes‐1 signaling

SM Radwan, GA Abdel‐Latif, SS Abbas… - Archiv der …, 2023 - Wiley Online Library
Methotrexate (MTX)‐induced hepatotoxicity is a serious adverse effect that may limit its use.
Therefore, eligible drugs to ameliorate MTX‐induced hepatotoxicity are required. l‐Carnitine …

Mangiferin mitigates methotrexate-induced liver injury and suppresses hepatic stellate cells activation in rats: imperative role of Nrf2/NF-κB/NLRP3 signaling axis

NM El-Sayed, ET Menze, MG Tadros… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Mangifera indica (family Anacardiaceae), often
acknowledged as mango and renowned for being a plant of diverse ethnopharmacological …

Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2

AI Matouk, EM Awad, AAK Mousa, SMN Abdelhafez… - Life Sciences, 2024 - Elsevier
Aim Gentamicin-induced nephrotoxicity limits its widespread use as an effective antibacterial
agent. Oxidative stress, inflammatory cytokines and apoptotic cell death are major …