Sex disparity for patients with cutaneous squamous cell carcinoma of the Head and Neck: a systematic review

B Tan, I Seth, O Fischer, L Hewitt, G Melville, G Bulloch… - Cancers, 2022 - mdpi.com
Simple Summary This is a systematic and meta-analysis of proportions study that
investigated the distribution of head and neck cutaneous squamous cell carcinoma between …

Molecular alterations in cutaneous squamous cell carcinoma in immunocompetent and immunosuppressed hosts—A systematic review

DA Tsang, SYC Tam, CC Oh - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most common
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …

Sex as a predictor of response to immunotherapy in advanced cutaneous squamous cell carcinoma

N Yeo, B Genenger, M Aghmesheh, A Thind, S Napaki… - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous squamous cell carcinomas (CSCC) are the second most
common skin cancer amongst Caucasians, accounting for up to 20–25% of skin cancers …

[HTML][HTML] Comparing genomic landscapes of oral and cutaneous squamous cell carcinoma of the head and neck: quest for novel diagnostic markers

R Gupta, D Strbenac, L Satgunaseelan, VKY Cheung… - Modern Pathology, 2023 - Elsevier
Squamous cell carcinoma is the most common head and neck malignancy arising from the
oral mucosa and the skin. The histologic and immunohistochemical features of oral …

[HTML][HTML] P53 and the ultraviolet radiation-induced skin response: Finding the light in the darkness of triggered carcinogenesis

C Carvalho, R Silva, TMVDP Melo, A Inga, L Saraiva - Cancers, 2024 - mdpi.com
This review delves into the significant cellular and molecular responses triggered by UVR
exposure in human skin, emphasizing the pivotal role of mutant p53 (mutp53) in the …

[HTML][HTML] Micro RNA Dysregulation in Keratinocyte Carcinomas: Clinical Evidence, Functional Impact, and Future Directions

J Conley, B Genenger, B Ashford… - International Journal of …, 2024 - mdpi.com
The keratinocyte carcinomas, basal cell carcinoma (BCC), and cutaneous squamous cell
carcinoma (cSCC), are the most common cancers in humans. Recently, an increasing body …

PIK your poison: the effects of combining PI3K and CDK inhibitors against metastatic cutaneous squamous cell carcinoma in vitro

JR Perry, B Genenger, AS Thind, B Ashford, M Ranson - Cancers, 2024 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is a very common skin
cancer with poor prognosis for patients with advanced disease. PI3K/AKT/mTOR and cell …

Evolution of head and neck cutaneous squamous cell carcinoma nodal staging—an Australian perspective

MJL Hurrell, TH Low, A Ebrahimi, M Veness, B Ashford… - Cancers, 2022 - mdpi.com
Simple Summary Australia has the highest incidence of cutaneous squamous cell
carcinoma of the head and neck (HNcSCC) in the world. Although the majority of HNcSCCs …

[HTML][HTML] Dysregulation of mRNA expression by hsa-miR-186 overexpression in arsenic-induced skin carcinogenesis

M Banerjee, A Lykoudi, JY Hwang, J Pan… - Toxicology and Applied …, 2025 - Elsevier
Dysregulated miRNA expression contributes to development of arsenic-induced cutaneous
squamous cell carcinoma (cSCC). hsa-miR-186 (miR-186) is overexpressed in arsenical …

Ex vivo therapeutic screening of metastatic cSCC: A review of methodological considerations for clinical implementation

J Conley, JR Perry, B Ashford… - Experimental …, 2024 - Wiley Online Library
Cutaneous squamous cell carcinoma (cSCC) is the second most common malignancy
worldwide, with most deaths caused by locally advanced and metastatic disease. Treatment …