The field of Green Chemistry has seen many scientific discoveries and inventions during the
20 years since the 12 Principles were first published. Inspired by tree diagrams that illustrate …

The molecules of today—the medicines that cure diseases, the agrochemicals that protect
our crops, the materials that make life convenient—are becoming increasingly sophisticated …

Abstract Background The Chemistry Development Kit (CDK) is a widely used open source
cheminformatics toolkit, providing data structures to represent chemical concepts along with …

The oxidation of unactivated C–H bonds has emerged as an effective tactic in natural
product synthesis and has altered how chemists approach the synthesis of complex …

The divergent total syntheses of complex natural products from a common intermediate have
attracted enormous attention in the chemical community in the past few years because it can …

Covering: 2011 to 2022 The natural world is a prolific source of some of the most interesting,
rare, and complex molecules known, harnessing sophisticated biosynthetic machinery …

The generation of molecular complexity is a primary goal in the field of synthetic chemistry.
In the context of retrosynthetic analysis, the concept of molecular complexity is central to …

Conspectus The preparation of complex molecules (eg, biologically active secondary
metabolites) remains an important pursuit in chemical synthesis. By virtue of their …

Detailed herein are our synthetic studies toward the preparation of the C18-and C19-
benzenoid cephalotane-type norditerpenoids. Guided by chemical network analysis, the …

Concise syntheses of the Cephalotaxus norditerpenoids cephanolides A–D (8–14 steps
from commercial material) using a common late-stage synthetic intermediate are described …