American Trypanosomiasis is an important neglected reemerging tropical parasitism,
infecting about 8 million people worldwide. Its agent, Trypanosoma cruzi, exhibits multiple …

Considering the extensive and widespread impact on individuals, cancer can presently be
categorized as a pandemic. In many instances, the development of tumors has been linked …

Because of its capacity to increase a physiologic inflammatory response, to stimulate
phagocytosis, to promote cell lysis and to enhance pathogen immunogenicity, the …

Chagas' disease is a zoonotic parasitic ailment now affecting more than 6 million people,
mainly in Latin America. Its agent, the protozoan Trypanosoma cruzi, is primarily transmitted …

Trypanosoma cruzi causes Chagas disease, a neglected disease that can be divided,
overall, into acute and chronic phases. Understanding the mechanisms underlying its …

To successfully infect, Trypanosoma cruzi evades and modulates the host immune
response. T. cruzi calreticulin (TcCalr) is a multifunctional, endoplasmic reticulum (ER) …

Calreticulin (CRT) from vertebrates is a calcium-binding protein present mainly in the
endoplasmic reticulum (ER). There, it directs the conformation of proteins and controls …

In Latin America, there are about 10–12 million people infected with Trypanosoma cruzi, the
agent of Chagas' disease, one of the most important neglected tropical parasitism …

Eight to 10 million people in 21 endemic countries are infected with Trypanosoma cruzi.
However, only 30% of those infected develop symptoms of Chagas' disease, a chronic …

American Trypanosomiasis, a parasitic disease produced by Trypanosoma cruzi (T. cruzi),
endemic in Latin America, infects about 6 million people. During the chronic stage of the …